CLUSTAL format seed alignment for MF_01006
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
UPPP_BIFLO -----------MNFFQAIILGIVQALTEYLPVSSSA-HIRIFGDLMLG-----------S
UPPP2_STRAW -----------MSWFESLILGLVQGLTEFLPVSSSA-HLRLTAAFAGW-----------E
UPPP_CHLTE -----------MNLFQAIILGIIQGLTEFLPISSSA-HLRIVPALMGW-----------G
UPPP1_STRAW --------MSVINVGQAVVLGAVEGVTEFLPVSSTG-HLKITEGLMGIP--------VDD
UPPP_CORDI ---MTQDPSSQISWSQTIVLSIVQGLTEFLPISSSG-HLRIVSELF-----------WGK
UPPP2_RHILO ----------------------MQGITELLPISSTA-HMRIVPALLGW----------QD
UPPP_GLOVI -------MQQQIGIFEAIVLGFVQGITEYFPISSTA-HLRVVPALLGW----------AD
UPPP_PARMW MADPSASLGLWEACWRDLVLGIVQGLTEFLPISSTA-HLKVVPVLLDW----------GD
UPPP_THEVB --------MDIILWLQAVILGLVQGMTEFLPISSTA-HLILFSDLLGW----------KS
UPPP2_CHRVO -----------MNAIEALLFAVIQGVSELFPVSSLG-HGVLIPDWL------HWSINRTH
UPPP_MYCPA -------MTAHLSYVEAVVVGAFQGVTELFPVSSLG-HAVLVPALVGGRWAQDLSVSAHR
UPPP_VIBVY -----------MSYFEAFVLALIQGLTEFLPISSSA-HLILPSAIL-----------GWE
UPPP_GEOSL -----------MDIMHAAVLGILQGLTEILPISSSA-HLILVPWLL-----------GWP
UPPP_PROMP -----------MEFFKYIFYGIIQGLTEFIPISSTA-HLKIISLLFGMD-----------
UPPP_SACS2 ----------MNYILIGVILGIVQGISEWIPISSKTQVLIVSSTLLGLSF----------
UPPP_SULTO ----------MNLLDI-IIIGIVQGISEWLPISSKTQVLISSHYLLNLPI----------
UPPP_PYRAE ----------MDLGVA-AILGVVQGISEWLPISSKTQIMLVSIWLLNASP----------
UPPP_PYRIL ----------MDFLTA-IVLGVVQGVSEWLPISSKTQVMFVSQLLLSATP----------
UPPP_METBU ----------MLSLSEAIILGIVQGLAEWLPISSEGMTSLVMVTFFGRSL----------
UPPP_METTP -----------MDALQALVLGALQGITEWLPVSSEGQTMLAMISWLGMRP----------
UPPP_THEMA ---------------MDLLLGIVQGLTEFLPISSSG-HLTLLSHLLKTD-----------
UPPP_METMP --------------MEELILGIVQGLTEFLPISSSG-HLAIFTALFNST-----------
UPPP1_HALH5 ----MEWSQELWLLIKYLLLGLFQGFTEPIPVSSSG-HLVLLQHFLGIE-----------
UPPP_OCEIH ----MNVFENFWTIVHYFVLGLVQGITEPIPISSSG-HIIIFRELFGIE-----------
UPPP2_HALH5 -----------MSIIEAIIIGIVQGITEFLPISSTA-HIVITQFLFDYT-----------
UPPP3_BACCR -----------MNWLEAFILGIIQGLTEFLPISSTG-HLYLGRHLFRLD-----------
UPPP_BACTN -----------MSWLEAMILGLIQGLTEYLPVSSSG-HLAIGSALFGIQG----------
UPPP_BORBU ----------MTNILSAIILGIIQGITEFLPISSSG-HLLLFRHFINLK-----------
UPPP_TREDE -----------MSIFQAIILGAVQGLAEFLPISSSG-HLAIVEYFFKQE-----------
UPPP_RHOBA ----------MQELIRVVILAIVQGIAEFLPISSSG-HLVILGSMLGEL-----------
UPPP_AQUAE -----------MTEWQAVVLGIVEGISEFLPISSTG-HLILTAHILGIK---------HT
UPPP_WOLSU -----------MDIFHAIILGIVEGLTEFLPVSSTG-HLILVSELLGIK---------QD
UPPP_PORGI -----------MTILQAIVLAIVEGLTEFLPVSSTG-HMIIAEGIMGVE---------ST
UPPP_BDEBA -----------MSYLHAIILGIVEGITEFLPISSTG-HMIIASSMMGIE---------DS
UPPP1_CLOAB --------MEHIEILKAIFLGIVEGITEWLPISSTG-HMILVNEFIRLN-V-------TE
UPPP_STRMU --------MLFFEIIKAIIFGIVEGITEWLPISSTG-HLILVEEFIHFNNA-------NA
UPPP_FUSNN ---------------MVVILAIVEGITEFLPISSTG-HMILVNKLIGGEYL-------SP
UPPP_BACSU --------MTLWELFVAAILGIVEGLTEYAPVSSTG-HMIIVDDIWLKSS-----NLMSE
UPPP_STAES --------MFLLELIKGIILGIVEGLTEFAPVSSTG-HMILVDDMWLKST-----NFLGS
UPPP_ECOLI -------MSDMHSLLIAAILGVVEGLTEFLPVSSTG-HMIIVGHLLG----------FEG
UPPP2_CLOAB ------MYTNLIFIFKIILEGIIEGVTEFLPVSSTG-HMIILGSIIGFKEGAKPVSLYGA
UPPP_CLOTE ----------MLLILKAIILAIVEGLTEFVPVSSTG-HLILVSDVINFK----------G
UPPP_CALS4 --------MKMELLIKAFIMGIVEGLTEFLPISSTG-HLIIVGSFIKFT----------G
UPPP_NITEU --------MDWLILLKALLLGIVEGLTEFLPISSTG-HLILAGDLLNFND---------D
UPPP2_SHEON --------MDLIYFIKAFFLGVIEGITEFLPISSTG-HLILIGDWINFSS---------N
UPPP_RHOPA ---------MLIDIIRAVILGIVEGVTEFLPVSSTG-HLLLAERFFNLGEG--------N
UPPP_DEIRA -----------MDWLYSLIYGIVEGITEFLPISSTG-HLILTGNLLHVPWP--------K
UPPP_XYLFT ----------MFELFTALMLGILEGITEFLPVSSTG-HLLIAEHWLG-------------
UPPP_LEPIN ----------MNPYLNAFLRSIIEAITEFLPVSSTG-HLFLFSSFFPFYGE-------NV
UPPP_BUCAP -------MFFFHKIVIPIIIGIIQGITEFFPVSSTG-HMIIFIDWLDIK----------N
UPPP_BUCBP -------MTMTTNIFNAIILGIVEGITEFFPISSSG-HLLIFTNILEMK----------N
UPPP_WIGBR ----------MKEILIIIILGIVEGITEFFPISSNG-HLILINYIFNID----------K
UPPP_TROWT ------------MVLEAVLLGIVQGITEFLPISSTA-HMYILAKLLNLH-----------
.:..:* *:**
UPPP_BIFLO DPGAAFTAIIQIGTELAVILYFRHDIINILTHWFSCLFGKNGKDWKARMG--------RG
UPPP2_STRAW DPGAAFTAITQIGTEAAVLIYFRKDIARIISAWFRSLVNKEM----------------RH
UPPP_CHLTE DPGAAFTAIIQIGTLAAVLIYFAKDIVSISGAVISGLVKGKP----------------LG
UPPP1_STRAW NAVVGFSAVIQVGAIAAVLVYFFKDIVRIVSAWGRGLRNRDE----------------RH
UPPP_CORDI DAGASFTAVVQLGTEAAVLVYFAKDIAKILTGWFRGLFDKKQ----------------RG
UPPP2_RHILO P-GSAFSAAMQLAALAAVISYFWGDVRDLLFGSLDALTRRDFS-----------------
UPPP_GLOVI P-GTAYSAVIQLGSLLAVLTYFYKDLVEILSGTVRALRTGDTQ-----------------
UPPP_PARMW P-GVSVTAAIQLGSIVAVIAYFRRDLAQVMQGISKAFRHGQWR-----------------
UPPP_THEVB IWHKTALDAMQFGSVIAVLGYFWQDIHQIVQGSWQAWQRRDWQ-----------------
UPPP2_CHRVO PDFLPFMVMLHLGTAAALLIYFRRDWVDLIGGWLKA--GGRASNP---------------
UPPP_MYCPA SPYLAFIVGLHVATAAALLVFFWRDWVRILAGFFSSLRHRRIRTP---------------
UPPP_VIBVY DQGLAFDVAVHVGTLAAVVIYFRKEVITLFAALFASIFKGERSK----------------
UPPP_GEOSL ESGLTFDVGLHVGTLIALCVYFRRDIAYLISDAITGLREGFGSQ----------------
UPPP_PROMP DPGSSVSAIIQIGSVFAIFWYFRKSISNYKNTNSRKPSYSFLF-----------------
UPPP_SACS2 NVAYSFGLFMEIGTIAAAIFYFRSEISGLLKALVRMSSRRE-------------------
UPPP_SULTO AIAYSFGLFMEMGSIGSATIYFRKDIMSVFR-----------------------------
UPPP_PYRAE EYAYSLGLFLEAASVLAALIYFRGVYLKALRGFVGDAE----------------------
UPPP_PYRIL ELAYSLGLFLEAASVLAALIYFRLVYLKILRGFLGDAE----------------------
UPPP_METBU SEAIPISIWLHLGTLLAAIVYFREDVKVLLYGVPDYVRSFS--RK---------------
UPPP_METTP TDALSCSIFLHTGTMLAVLVRFRSRLLGMLNTESKLMRTV--------------------
UPPP_THEMA -LNAYQTAVLHLGTLVSVVLFALDGI--------RRSLRSW-------------------
UPPP_METMP -PDVGYFAFLHLATFLAVLIFVKAEVFEIITGITKKETEYI-------------------
UPPP1_HALH5 IEGLSFEVMVNFASLFAVIAIYRFDLLKLVKGSARYVLYQD-AQG---------------
UPPP_OCEIH ARGLSFEIFVNLASLLAVLIIYRKDIVRLAVNSWNFIFKQE-KES---------------
UPPP2_HALH5 FPGFGFEIFLHIASILAVILYFRKDLLQVIVGFFSYFKDKS-EEN---------------
UPPP3_BACCR EAGLFLDTMLHIGTLLAVFIYYKKEFIYLIKNPF--------------------------
UPPP_BACTN EENLAFTIVVHVATVCSTLVILWKEIDWIFKGLFKFQMND--------------------
UPPP_BORBU -LSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVKSD---------------
UPPP_TREDE DLPILFDILLHVATLAAVCTVFAKRIAGLFSVLGRFIIRKSKPED---------------
UPPP_RHOBA GESVTLEIILHAGTLGSILVVFWQRIWALLLKDR--------------------------
UPPP_AQUAE DFVKSFEISIQLGSILAVVVLYFNRL----------------------------------
UPPP_WOLSU DFHKTFEISIQLGSILAVLALFRERL----------------------------------
UPPP_PORGI SFVRAFTVMIQFGAILSVLVLYRKRFFCFPVAPRALGQGKGKEF----------------
UPPP_BDEBA SFTKAFEVIIQFGAIMSVLVLYWKRF----------------------------------
UPPP1_CLOAB AFKQVFLVVIQLGAILSVVLLYFNKLIPFSLN------GGFYLK----------------
UPPP_STRMU AFTNMFNVVIQLGAILAVVVIYFDRLNPFKSG------KTAREV----------------
UPPP_FUSNN TFRNSFLIIIQLGAIFSVVVYFWKDISPFV--------KTKKEF----------------
UPPP_BACSU EAANSFKVVIQLGSILAVAIVFKDRILNLLGLKKNITSDQEQG-----------------
UPPP_STAES QSAFTFKVVIQLGSVFAAAWVFRERFLEILHIGQHKPEPSTSGDRR-------------S
UPPP_ECOLI DTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESK---------------
UPPP2_CLOAB EYIHMFEIIIQLGAILAIVVLYWDKIFSALKPSNLFPSMKEHEKSGIGVVGEFFVKGYNT
UPPP_CLOTE DYANLFNVVIQLGAILAVVVVYWDKLLNSVK--DIFAPDRR-------------------
UPPP_CALS4 KFATMFEIVIQLGAILAVVYYFKDKILSSLK--ALKPGEW--------------------
UPPP_NITEU KAK-VFTVAIQLGAILAVCWEYRERLVNIIRNLGTRQ-----------------------
UPPP2_SHEON EEK-VFEVVIQLGGILAVCWLFRDKIINLINGVLKSDPV---------------------
UPPP_RHOPA FWK-SFAVLIQLGAILAILALYFVKLWRIALGMFTDAN----------------------
UPPP_DEIRA EVKDTFEVVIQGGAILAVLVYYWRDFLKIRHIGHDRG-----------------------
UPPP_XYLFT SRSDFFNIVIQAGAILAITFVFRKKVWSLATGLDKYSNRD--------------------
UPPP_LEPIN EFDDLFDIFIQSGAILSVLFLYREKFKSQIVSSFRYILKQNSDSEG--------------
UPPP_BUCAP KDTKILEIFVQLGSTISVFLFFYKKIIQILQLPMQK-ESNEKKN----------------
UPPP_BUCBP NEIKILNTIIQTGAALSILLHFKEKFVIFLEQIFIC-KQITKKND---------------
UPPP_WIGBR ENIQNIIKIIQIGPIFSIILLFKEKIKKSITFFYFNINNIKKKLI---------------
UPPP_TROWT VPGRFFLSSVQLGTSFALILYFFKDVKGIISETSRSIYSFIQFGIRQKQG--------KR
. .
UPPP_BIFLO DNYATLGWNIIVGSIPIIILGFTLQNVIETS-------LRNLWITVTVLLVFGILLWMVD
UPPP2_STRAW DHDAQMGWLVIVGSIPIGVLGVTLKDQIEGP-------FRDLRITATMLIVMGVILGIAD
UPPP_CHLTE TDEARTGWMIAVGTIPIVVFGLTFKHEIETV-------LRSLYIVSASMIGLALVLVVAE
UPPP1_STRAW HHDYKFAWWVIYATIPIVIVGLAAKSLIEGP-------LASLWVVAASLIVGSGVMWAAD
UPPP_CORDI -FDYRMGWMVIVGTLPVSIVGLLAKDIIRDN-------LRNMWITASVLIAFSFVFIAAE
UPPP2_RHILO DRHFRLASWIVLATIPIVIAGVALSGVLNAC--NS--PLRSLTVIGWSCIAMAILLALAE
UPPP_GLOVI SREVRLFWGIILGTIPIVIAGLALKSTLEAP--GS--PLRALSVIAVASIVMAALLWLSE
UPPP_PARMW EPEARLGIAMAVGTLPILAVGLAIKLFWDEGYETS--PLRSVPSIAVVSIVMALLLAVAE
UPPP_THEVB REEWKLLLGITVGTIPALAAGLLLKLA------KV--ELDRPQIIATMAIAMAILLGLAE
UPPP2_CHRVO --HARLMWLVIAGTLPAGLLGLLLEKQLRAL------FASTTAVLVFLALNGLLLLWGDK
UPPP_MYCPA --DERLAWLIVVGTIPVGLAGLALEQLFRTT------LGKPVPAAAFLLLNGVALYAGEV
UPPP_VIBVY --EAKLAWMIVIATIPACIFGLVMKDVIEVY------LRSAY-VIATTTIIFGLLLWWVD
UPPP_GEOSL --TSRLPFFIIAGTVPAAIAGKTLEKPIEEF------FRGSHTLIALLLIAFGLLLALAD
UPPP_PROMP ---NKLNKSIFIGTIPIVFIGVIIKLFVPGF-SDS--FLRSNLSIALVSILMSLIMLFAD
UPPP_SACS2 --DYLLLKFLVIVTIITGLVGVPLYLFVISLPI----LGLPMTVLGVVLLIDGIVIYLSR
UPPP_SULTO --DRKLLLYLAIITIITGLVGVPLYIISDKLLKNAYDPSIPMIILGIALIVDGLYIRYSR
UPPP_PYRAE --GRRWLVYILVTTLVTAVVGLPLYYVARKWLVVGHSAGFLMIVLGLAVVLNAVFLQRAR
UPPP_PYRIL --GRKWLTYVIVTTAATGAVGIPLYMAAKRYLLLGASAGWLMVVLGVAVIFNAVLLQRAR
UPPP_METBU QPHDPVISFLLISTALTGIVGLPLLLFVTDNVEIS--GGSATAVIGIMLIVTGILQRTVS
UPPP_METTP ----------IVATLFTGITGVPLYMLFRDRFTG---GEQATLLIGSLLIATGLMLRLRS
UPPP_THEMA ----RIILNLIVSTIPAGVFGVLFEKQIDQLFSSP-------RFLPLFFSATALILMFTR
UPPP_METMP ----NLASKLVLSTIPAVIVGLCFGDFIESVFSST-------LLIGVFLSITGILMLLSD
UPPP1_HALH5 KGDFRISFYLLLATVPAVLAALLFKDWIETELKQ--------LHVIAFALLITGMALWLI
UPPP_OCEIH KSDFMFVVYLVLATIPVGIVGVLFGDEIGAFIGEDG------TTVVGITLLITAAAIWMI
UPPP2_HALH5 RIQFMFAIYIIVATGITGVLGLLLEDLVGAQMKTPP------FIAGALIITGTFLIIIER
UPPP3_BACCR ---SKLMLLLIVGTIPAVVIGLLFKDFFEDISKTGI------TI-GWEFLVSGFFLYMAD
UPPP_BACTN --ETRYVINIVISMIPIGIVGVFFKDYVEAIFGSGL------MIVGCMLLLTAALLSFSY
UPPP_BORBU LTNLKLILLILIITIVTGVVGTFISKYESMFTLS----------FVLINFIITGILILML
UPPP_TREDE KDDLMMIAAIIVATAVTGVIGLLLKDWVKTIDIR----------LIPIFFIITGLLLIAS
UPPP_RHOBA ----RVIGLLVIGTLPAVVIGLTIKTQFPEILRSP-------LLAGAMLIVTGVMLIVLG
UPPP_AQUAE IRDYEIWKRIIAAFIPTGIIGFLLYKLIKGFLIGND------LVVVVSLILGGIILIFAD
UPPP_WOLSU FSGVDIWLKLAVAFIPTGALGFLLYKHVKALFAPS--------TVAYALILGGIVFLVLE
UPPP_PORGI MSRFDLYWKLLIALVPAVILGFLFEDWVDRMLGSV-------WVVAVVLFLGGIFMLFVD
UPPP_BDEBA LPHWGFYRKLFVAFLPTAIIGFVVKDVVEHLMGSV-------QVVAWSLIIGGVILIWAD
UPPP1_CLOAB KDVVSMWIKIIISCIPATIVGIPFDDKIDALFY-NY------QTVSITLISFGILFIMIE
UPPP_STRMU QITWQLWAKVILSALPAAVIGLIFDDWLDAHFQ-NF------FSVALMLILYGIAFIYVE
UPPP_FUSNN VLKFRLWLKIIVGVLPAMVIGLLLDDIIDKYFLDNV------LIVAITLIAYGVIFIGIE
UPPP_BACSU --HKLSIAQIAVGLVPAAVLGFLFEDYIDEYLFSV-------KTVAIGLIAGAILMLFAD
UPPP_STAES KPRRLNLIHVLVGMVPAGILGFLFDDLIEKYLFSV-------PTVLIGLFIGAIYMIIAD
UPPP_ECOLI --GRLTLIHILLGMIPAVVLGLLFHDTI-KSLFNP-------INVMYALVVGGLLLIAAE
UPPP2_CLOAB MPGFKFWTNIVVACIPAIVIGLPFQKKIDKLLFFP-------APVAAALMVGAVWMIFAE
UPPP_CLOTE --GLRFWINIVVACIPAVIFGFSLDDYIDKYLFNP-------ITVAIGLVIGGILMIIVE
UPPP_CALS4 --GFNLWYKTFIAFLPAAIIGILTHHYIEEHLFSP-------FTVAIALIVGAIMMIVIE
UPPP_NITEU --ANRFVINLFIAFLPAAILGLLFIKTIKHYLFHP-------MPVAIALVTGGILILWAE
UPPP2_SHEON --AQRFAVIVMISFLPSAIIGALFIHDIKNVLFNT-------TVVATALIVGGLIILWVE
UPPP_RHOPA --ARRFVIGVLVAFLPAAVIGAAFGGYIKHYLFNP-------WVVCFSLIVGGAILLWVD
UPPP_DEIRA --QQRLWLGVVLACIPAVILGVLFGDTIKAYLFRP-------SVVAWALIVGGVLMWLLE
UPPP_XYLFT -----YVMKLATAFLITAVVGLAVRKANWQLPETI-------QPIAWALIIGGIWILIAE
UPPP_LEPIN FHFLIQICIGAFPILIAGFIAKKFLDTIKARPDLL-------EILSGAWIFGGVLILVAE
UPPP_BUCAP -------IHVLISILPTMFLGLIFYNKIKSLFNPT--------NVMYALILGGFFLIIAE
UPPP_BUCBP ----LIYHHIILGNIPIIFIGLCIYQYIKYLSNFY--------SIIYALIFGTILLILTE
UPPP_WIGBR ----LILFNLVLSCIPISILGFMFYKKLEEFYSPK--------YISYFLILGSIFFILSE
UPPP_TROWT NEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGFFSAA---RNLFTMGVALIVFGLLLGFAD
.
UPPP_BIFLO AKARQN---------------------KTMNDMTYRDAFLFGLGQSMALI-PGVSRSGGT
UPPP2_STRAW RLAARDETGGKHRAAKER---------KKLQDLNIRDGLVFGACQAMALI-PGVSRSGAT
UPPP_CHLTE KHTANRARDGRRG--------------KSINELSWTDAIIIGLAQAMALI-PGSSRSGVT
UPPP1_STRAW QMGRHK---------------------RGEDDTSFKDAMLVGSSQILALLFPGFSRSGAT
UPPP_CORDI KWGSKR---------------------RSFDQLTMRDAVIMGCAQCLALI-PGVSRSGGT
UPPP2_RHILO IFARHK---------------------RTIAEASLADALLVGVAQIGALI-PGVSRSGST
UPPP_GLOVI SLGKRT---------------------RTMKGIRVIDGILIGCAQALALV-PGVSRSGST
UPPP_PARMW RMGPRR---------------------KQLSDVSGRDGLVVGLAQVLALI-PGVSRSGST
UPPP_THEVB QWGSRK---------------------RTYQDIGILDGFLVGCGQMIALL-PGASRSGST
UPPP2_CHRVO LKKKTAS--------------------HELSELSFAGAIKIGAGQALALL-PGFSRSGAT
UPPP_MYCPA LRRRVAPVADEPAVPDAEQQHGDEASDNRLAQLPLRRGVLIGAAQILALL-PGISRSGIT
UPPP_VIBVY KNASLLD---------------------DEYQAGWKKALFIGIAQALAMI-PGTSRSGAT
UPPP_GEOSL TTGPKRW---------------------RMDRVDLRGALLIGLAQCLALI-PGVSRSGIT
UPPP_PROMP ISTKKSI---------------------NLNNHKYPNNLYIGIAQAFAIV-PGVSRSGAT
UPPP_SACS2 KNYFPRKG---------------------LHDLKLRDIIIVGIAQGLAAL-PGVSRSGMT
UPPP_SULTO ---IKIRS---------------------FKDLSLKNIILIGIAQGLAAL-PGVSRSGMT
UPPP_PYRAE -FSAGLKA---------------------FDNMSLRDMAIVGIAQAVSVL-PGLSRSGAT
UPPP_PYRIL -SVAGLKT---------------------FDDMTLGHMALVGLAQALSVL-PGISRSGIT
UPPP_METBU ---RDESL---------------------SRVPGMSDSLVSGVAQGFAAI-PGISRSGIT
UPPP_METTP ---SSTKD---------------------MEEISTKDMVLLGLAQGFSIL-PGVSRSGTT
UPPP_THEMA YSSSGEKR---------------------MENMSFLDALLVGIAQLFALF-PGISRSGIT
UPPP_METMP NLNKNLKT---------------------IKSIPYWDALIIGVFQAFSVL-PGISRSGTT
UPPP1_HALH5 RHLNGRKQ---------------------DGDITLKDALLVGLAQTAALI-PGISRSGAT
UPPP_OCEIH RNLRGRKI---------------------EGDLSTKDAVIVGLAQAVAVT-PGISRSGAT
UPPP2_HALH5 FFVYKDRT---------------------VKDMTLKDSIIVGLGQTLAVF-PGISRSGAT
UPPP3_BACCR KQKNGRKK---------------------MDDITYKDALIIGSFQAAAIF-PAISRSGMT
UPPP_BACTN YYKPRQK-----------------------DKISMKDAFIIGLAQACAVL-PGLSRSGST
UPPP_BORBU EFNFLKVD---------------------FKGNILLAGIFMGLMQGLGAL-PGISRSGIT
UPPP_TREDE SKIKHNKQ---------------------AKNVTLLTAAITGLAQGIGVI-PGISRSGST
UPPP_RHOBA RLTPKSGT---------------------YDRLGLGAAFLVGCFQAFAIL-PGISRSGST
UPPP_AQUAE TYC------------------EKFCYLGDVRELPLRKAFMIGVFQSIAV-IPGVSRSGST
UPPP_WOLSU WLHK-----------------DKEYKINSVESIGYKEALAIGFFQALAM-IPGTSRSGST
UPPP_PORGI KLFA-----------------S-----SDRGEITYPKAFVIGLFQCLAIFLPGLSRSMAT
UPPP_BDEBA KAFA-----------------HLTMMGRKTDDLTYKDSVKLGLFQAIAM-IPGVSRSGAT
UPPP1_CLOAB NHNK-----------------GKHPRITSISEITYTTAVLIGIFQLIAAVFPGTSRSGAT
UPPP_STRMU RRHQ-----------------GVEPQVTHLVSLPYKTAFFIGLFQVLSLI-PGTSRSGAT
UPPP_FUSNN VVYKLK---------------NIKPKVKRFAGLKYRTAFLIGFFQCLAMI-PGTSRSGAT
UPPP_BACSU WVN------------------KRKTATDTLDRISYKQAIAVGLFQCLSLW-PGFSRSGST
UPPP_STAES KYS------------------KTVQHPQTVDQINYFQAFVIGISQAIAMW-PGFSRSGST
UPPP_ECOLI CLK------------------PKEPRAPGLDDMTYRQAFMIGCFQCLALW-PGFSRSGAT
UPPP2_CLOAB NKY------------------RKRAKIKSVDEITIKQAIVIGCFQCLALW-PGMSRSAST
UPPP_CLOTE NKY------------------RRRSKTKNIYDMKLRQSIFVGMFQCLALW-PGMSRSAST
UPPP_CALS4 DIF------------------GKKYKIDNMDKVSTSKAFWIGVAQVMSLF-PGMSRSAST
UPPP_NITEU RRE-------------------HRIEAETVDDMSWKQALQVGCAQCLALI-PGTSRSGAT
UPPP2_SHEON NRKD-----------------SEKFKIENIEKIGFKQAIIIGIAQCIAMI-PGTSRSGAT
UPPP_RHOPA QLD-------------------LKPRYHDATAFPLLTYFYIGCAQCTAMI-PGVSRSGAS
UPPP_DEIRA SRK-------------------ATPDTHDIENISAGKALAIGAAQCLALLWPGFSRSASS
UPPP_XYLFT SVAKH--------------------LPE-RENVTWSVAIAVGLAQVVAGVFPGTSRSAST
UPPP_LEPIN WYFHQ--------------------RPEEKKSIGFKDSILIGIFQCMA-LIPGMSRSAAT
UPPP_BUCAP KFKP------------------KKPKTNSIKEINLVQSLIIGCFQTLCLY-PGFSRSGAS
UPPP_BUCBP ISKT------------------KIS---SNKNIETPQILIIGIFQCLALW-PGFSRSCAT
UPPP_WIGBR FISL------------------KKIKIDNFKKISFLKYFIIGSSQCFSLL-PGVSRLGIT
UPPP_TROWT ALFRRKKG--------------------NIFQITFIESVLIGAAQVFAII-PGVSRSGIT
* * *. ** :
UPPP_BIFLO ITVGRALGYTRE-AAVRLSFLMAIPAVFGSGLLEAIKAVKNYKTDAMFPGWGPTLVAMVI
UPPP2_STRAW ISGGLLIGYTRE-SAARYSFLLAIPAVLASGVFELKDAAASGHV-----AWGPTVFATVI
UPPP_CHLTE ITGGLFRNLDRE-TAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTH--NMLNLAVATIA
UPPP1_STRAW MSTALILDLDRV-AATRLSFFLGIPALTGAGLYELKDALGTGVGVAP------LAVGTIV
UPPP_CORDI VSAGLFVGLDRE-VATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAAS--GMQLAVGTGI
UPPP2_RHILO LTAALGLGFKRA-EAARFSFLLGLPAIALAGLKELWELHKVHLDAH---GWSVLATGLVV
UPPP_GLOVI LTAALFLGFQRA-DGARFSFLLAIPAIFLSGLLELKVLVDEGFSG----GIGPIVAGFVS
UPPP_PARMW LTASLLDGWQRA-DAARFSFLLGIPAITIAGIVELKDALAATADA----GPLPLVIGILA
UPPP_THEVB LAAALALGLERP-TAARFSFLLGIPTLTIATLVQAKDVFDEGTLL------IPLVIATLS
UPPP2_CHRVO LVAGLAHGLDYA-SSARFSFLLATPIITAAGLLEIPKLAHRGNGSA---EWGLLLACGAV
UPPP_MYCPA IVAGLWRGLSHE-DAARFSFLLATPIILAAGVYKIPELFGP-LGAG---IGGQVLAGSIA
UPPP_VIBVY ITAALYLGFTRE-AAARFSFLMSIPIITLAGSYLGLKLVTSGEPV----HVGFLLTGIVT
UPPP_GEOSL ITAALFLGFTRD-TAARFSFLLSLPIVAGAGILKMGELARHGIPAG---ELAPLLAGMAT
UPPP_PROMP ISMALLSGWNRK-DAAKFSFLLGIPSISLAAFVEFFSAVNQFSTFP----FLPLFAGLIT
UPPP_SACS2 TSALILLGVKPE-EAFKLSFISLIPAALGAISVTVLFSKHEVSQAVHSVSLSGLLISIVV
UPPP_SULTO VSTMLFLGIKPD-DAFRYSYLAYIPAAVGAVGTTILFSKTNISYVISLIGIGGVLISVIS
UPPP_PYRAE VTALLLLGYKPE-EAFRASFVLVPVAGLGATALAYLSEG-------GAVATAEALLAMAI
UPPP_PYRIL TTTLLLLGYRPD-EAFKSSFVLVPIAGLGATALAYLSEG-------GAVATPEVITAMLI
UPPP_METBU MSALLLRKFDAA-DAIRLSFLMSIPAVLVAEIGVGLMG--------MVELDINSIVGLFF
UPPP_METTP LTVLLMRGVKQD-DALMVSFIISVPAVLGAIALDCLAGSP------LSIRSLPGAVMLAS
UPPP_THEMA VSSLLFMKYRSE-DALQYSFLMSIPVVLGAGILGLGK---GNV----------TILAPIF
UPPP_METMP LFAALFLGMNKE-DAVKYSFLMSLPVTFGAGILELQKITFSSE----------QLFGFVI
UPPP1_HALH5 IVAAMGLGWRQE-TALRFSFFLYIPISLGSGVLAISDIVQDPH--FTALW-IPYTIAFIG
UPPP_OCEIH LVASMLMGMKQD-TALRFSFLLYIPVSLGSSILEIPNIVRDPN--VQELW-IPYLVAFIT
UPPP2_HALH5 LITALFSGLNKE-TAVRYSFLLSIPVILGTSVLAIGDLLDGTL--VEQVGGLPLIISFIV
UPPP3_BACCR IVAALWRKLDRE-TAAYFSFLLSTPAIVGAIILQFVDVFQGK---AESISSTSLIVGTLS
UPPP_BACTN IATGLLLGDNKA-KLAQFSFLMVIPPILGEALLDSVKMMKGEDV-VGDIPALSLIVGFLA
UPPP_BORBU IFSASVIGFNRK-SAFEISFLSLIPIVFGAILLKHKEFYDIFM----VLNFFEINLGALV
UPPP_TREDE ISASLFAGLDRE-KAGEFSFLLSIPAILAAFILEIKSADNLLA----GVSPISLISGMIS
UPPP_RHOBA ILGGRLMGLDRD-DSVTFSFLLAIPAILGATVLAIKDLLEDGS--SGETSIEVLSIGAAV
UPPP_AQUAE IIGGMLMGLNRK-VAAEFSFLLAIPTMFAATTYDLIKSGGS----FNAQEWNILIIGFIT
UPPP_WOLSU IVGGLILGLNRK-VAAEFSFLLALPTMFIATGYDLYKNSHT----LSIENLSALGVGFVV
UPPP_PORGI IVGGQQQKLSRK-AAAEFSFFLAVPTMLGATLLKAYKLYKEGGIEIFREHMTVLLVGNIV
UPPP_BDEBA IMGGLTLGMNKK-EAAEFSFFLAVPTMAAATLYKLLKIYKT----IEPAQINLLLVGCAV
UPPP1_CLOAB IVGALLIGVSRT-VAAEYTFFLAIPVMFGASLLKLFKF----GLHFTSTEITILFIGMLS
UPPP_STRMU ILGGILLGTSRQ-VATEFTFFLGIPIMFGASLVKVLKFIVS-GTILTGSQLFILLVAMLV
UPPP_FUSNN IIGALLLGLSRP-LAAEFSFYLAIPTMFGATALKLFKN----GLAFTEMEWSYLALGSAI
UPPP_BACSU ISGGVILGLNHR-AAADFTFIMAMPIMMGASFLSLVKHWDS----LSSDLMPFFIVGFIC
UPPP_STAES ISTGVLMKLNHK-AASDFTFIMSVPIMLAASGLSLLKHYEY----IHLAHIPFYILGFLA
UPPP_ECOLI ISGGMLMGVSRY-AASEFSFLLAVPMMMGATALDLYKSWGF----LTSGDIPMFAVGFIT
UPPP2_CLOAB IIGAWIVGVATV-AGAEFSFFLAIPMMLGASLLFLIKNSVV----LSSVQILGLAVGFIV
UPPP_CLOTE IMGGWIAGLSPV-VAAEFSFFLAIPVMVGASGLKLVKSGFY----MTNIEFIALIVGFVG
UPPP_CALS4 IMGGMLVGLSVR-AAAEFSFFLAIPTMLAATGFELVKNITS----MSLLEWEALAVGFIM
UPPP_NITEU IIGGLLFGLSRK-AAAEFSFFLAIPVMFAATFYDVYKHREF----LYIDDLGMFATGSVA
UPPP2_SHEON IVGGMLSGVSRK-AATEYSFFLAIPTMLGAAIYDASKNYHL----LNTDDILAILIGFSA
UPPP_RHOPA IVAAMLLGTDKR-SAAEFSFFLAIPTMLGAFVYDLYKNHAD----MTADNLIIVAIGFVV
UPPP_DEIRA ILGGMLLGLDRP-TATKFSFYLGVPTLGGAALLDFIKSREI----LAQIGVVNVAIGAVT
UPPP_XYLFT IFLAMLLGLSKRSAAAEFSFLVGIPTMFSASSYACFELFKRGE--LLHENWLEVSVAFVA
UPPP_LEPIN IITARFLGKDTK-SSAEFSFFLAVPVLLAAGIYKLIKY--RSI--LNGNTIPVLMFGFLV
UPPP_BUCAP IAIATLLGFKRS-VAVNFSFIISIPLIAGASVLDLIKNIQNVNM----LNIPYLFSGFTI
UPPP_BUCBP ISAGILSGLKQS-KSVEFSFILSVPIFFGASVLDVINNFYDISI----NNIPMLFSGFLS
UPPP_WIGBR ISIGLILNIDRY-VLFKFSMILFSSIMPAVLILEVYKNFFYLK-----ENIFFVIIGVMS
UPPP_TROWT ITTARFLNFDRQ-LAVRFSFLLSLPVTFIGGMYGLVAGPDTDYY-----SLGYSLIGAIV
:
UPPP_BIFLO SFVLGYIVIIGFLKFVSN---FSYKAFAIYRIGLAVVVALLLIVGVLPAIDPSVVAAA--
UPPP2_STRAW AFVSGYAVIAWFMKFISN---KSFMPFVWYRIALGIAIIALVATGALSPHAAESAG----
UPPP_CHLTE AFIFGYLSIAFLLNYLKR---HTTGIFIAYRLILGIGLIVMIGTGHLLP-----------
UPPP1_STRAW SFVVAYGSISWLLKFVAK---HSFNAFVIYRIVIGVLLLGLLGTGVLS------------
UPPP_CORDI AFALGYASIAWLLKFVGS---HSFSWFAAYRIPVGLLVMALLATGMLTA-----------
UPPP2_RHILO ASISAFFAIWGLMRVLER---FSAWPFVIYRGLLGVVLLLGLAMGWLA------------
UPPP_GLOVI STVFSYLAIAWLLKFLQT---RSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP
UPPP_PARMW ATVVSWLAIDWLLKFLQR---HSTWLFVAYRLLFGVGLLAWWSIHGAH------------
UPPP_THEVB SMVFSYLAIAWLLQFLQR---HSTWVFIWYRIGLGSALWGAIALGSLQS-----------
UPPP2_CHRVO SGLCAYASTWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV----------------
UPPP_MYCPA SFVCAYLAVRYLTRYFQT---RTLTPFAIYCAVAGGASLVWLALR---------------
UPPP_VIBVY SFISAYLCIHLFLKMISR---MGMTPFVIYRLILGVGLFAYLLMA---------------
UPPP_GEOSL SAVSGYLGVALLLRLVQR---YSLYPFVWYRLLAGGAVLAYLFAR---------------
UPPP_PROMP AFFSSLLAINFLIKYVSS---HGLKIFVYYRLIFGILILFNL------------------
UPPP_SACS2 ATFVSIFFINALLRFART---NKVVLLVIILGIMAIISGILSDIAKGFY-----------
UPPP_SULTO AFIIGMLTIDLLLRFAKR---RNIYIIDFTLGGIAIVVSVLTILI---------------
UPPP_PYRAE GIVISIITIKALLEFAKS---KHVVLVNVVIGLLAIAGGLLRIIF---------------
UPPP_PYRIL GLVVSLVTIKALLEFAKS---KHVTLVNIVVGTLAIAGGITRILLSS-------------
UPPP_METBU AFAFGLVTIDLFLKVAKK---VDFSYFCIGLGVLSVLTMFL-------------------
UPPP_METTP SFITGYATMDVLMRFSRN---VSFSWFCITMGMITLALTALPEVQ---------------
UPPP_THEMA AFLSGLFALYVLSRSVRS---GKIWQFSYYCLFVAILSYLAG------------------
UPPP_METMP SFLTGLLGLYLVKKMVIG---GKLKIFGYYCFLASFFVIMFL------------------
UPPP1_HALH5 SFIASYVSLLWFMNIMRH---GKLIYFALYCWLAGLIVLSLLS-----------------
UPPP_OCEIH AFIASYFALKWFMNIMRH---GNLKYFAYYCVIVGVLVLIFL------------------
UPPP2_HALH5 TFFFSWLGIIWLIDFLKR---SKLIYFAFYCFALAIFVFFYFDHNMTIDLE---------
UPPP3_BACCR AAFFGYIAVSWMIQYLKR---HSLKVFAYYVWGLGILILMLQFTDVF-------------
UPPP_BACTN AFVAGCLACKWMINIVKK---GKLIYFAIYCAIAGLAVIITQL-----------------
UPPP_BORBU AFVVGIFSINFFFKMLNN---KKLYYFSIYLFALSI-IVCYFVRI---------------
UPPP_TREDE AFVVGYFSLRFLLKLIKN---GKLMYFAFYLIPLGLGLSIYFWGFAG-------------
UPPP_RHOBA AFAVGIVALKWLIRWSRE---DRLHWFAYWCIPAGLLVVLLNLR----------------
UPPP_AQUAE SFITALIVVKWFLNFLKS---HSLKIFGFYRILIGLVYAAFFLF----------------
UPPP_WOLSU AFIFAMIAVKGFLKFISR---FNFVPFGIYRIILGIIFLFYLDLI---------------
UPPP_PORGI AFIVALAAIKFFIGFLTR---YGFKAFGYYRILVGGLLIVLMLSGVSLAV----------
UPPP_BDEBA AFVVAMIAIKFFIGIVSR---YGFRGFGYYRIVLGLVILILLYTGHDLQMV---------
UPPP1_CLOAB AFIVSILAIKFLMIYIKR---HDFKAFGWYRIILGCAVLVYFLIV---------------
UPPP_STRMU AFAVSLYVIRFLTDYVKN---HDFTFFGKYRIGLGILLLFYGLMKVLFG-----------
UPPP_FUSNN AFVVAYIVIKWFMDFIKK---RSFASFGLYRIILGIIVIVLLY-----------------
UPPP_BACSU AFVVALFVVRFFLRLINK---IKLVPFAIYRIILGVILLLIMM-----------------
UPPP_STAES AFIVGLIAIKTFLHLINK---VKLVPFAIYRIVLVIFIAILYFGFGIGKGI---------
UPPP_ECOLI AFVVALIAIKTFLQLIKR---ISFIPFAIYRFIVAAAVYVVFF-----------------
UPPP2_CLOAB AFIVALVVVDRFISFLKK---KPMRIFAVYRLAIGIIVLVLGFTKVIS------------
UPPP_CLOTE AFLVSLVVIEKFIKFLQK---KPMRIFAIYRIFIGAILLILAIFKIVTI-----------
UPPP_CALS4 SFITALIVVDKFLAYLKR---HVLKPFAYYRLLVGVLMLFLIAQKIVK------------
UPPP_NITEU AFISALIAIRGFIRYISH---HDFTLFAWYRIGFGLIVLLTAYSGLVDWSVD--------
UPPP2_SHEON AFISALIVVNALIRFVAK---HSLSVFAWYRIALGLIIFSVN------------------
UPPP_RHOPA SFITAIIVVKTFLTYVTR---HGFELFAWWRVIVGTLGLIALALGL--------------
UPPP_DEIRA SFVVAYFAIGWLLRFVST---NNFKGFAVYRVVVGVLILVLIARGVLQNGSLA-------
UPPP_XYLFT AMLTGFAVVKWLLGYIKN---HSFAPFAYYRIALGLVLLTWLT-----------------
UPPP_LEPIN SFLLCTLVIRWFLRYIQK---HSFSVFGVYRILLGVGVLVLTKLI---------------
UPPP_BUCAP SFIISFLLIKKFITILNK---VSLTFFGIYRFLIAGIIYFI-------------------
UPPP_BUCBP AFITSNIVIKRCLNTMKN---CSLIPFIIYRSILSIIIYLFFMH----------------
UPPP_WIGBR SFLTSLIFGRTAIKIMKN---TSLIIFAIYRIFIACIILFTCN-----------------
UPPP_TROWT SFVVGLLVVSALLRIISK---TTFVLFVYYRVLFGLFLVIVSFF----------------
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