CLUSTAL format seed alignment for MF_01211
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
PYRK_CLOAB --MKEKYTVEKVYENIKVEDGIYKLSIKGEFEVRPG----QFYLLRAWDIEPTLSRPISI
PYRK_CLOPE --MAMEYFKGKVKENIELVEGIYSLVVEHEAKINAG----QFYMIKT--PNTFLGRPISV
Q18CS7_CLOD6 --------MYKILENIYIGEDMYRMKVKGNFEGKMG----QFYMLRAWDTYPVLSRPISI
PYRK_CALS4 ---MRWKMKARVLSNRRIASEVYEMTFEWKGKKPHP----GQFLMIDCQGKTFLKRPFSV
PYRK_BACCL ---MIGRERMTVASQRLIAERTYELTLSGRLVQEMRQPGQFVHVKVAASADPLLRRPLSL
PYRK_HALH5 ---MRQTERMTITSHQRIADGIYEMKVTGERVKEMTSPGQFVHVKVDDGSELLLRRPLSI
PYRK_BACSU ----MKKAYLTVCSNQQIADRVFQMVLKGELVQGFTTPGQFLHLKVSEAVTPLLRRPISI
PYRK_LISIN ----MLQTEMKVIQQTEIADKVYELILSGECVADMS-PGQFLMLKPSRS-DLLMRRPISI
PYRK_LISMO ----MLQTEMKVIQQTEIADKVYELILTGECVAGMS-PGQFLMLKPSRS-DLLMRRPISI
PYRK_LACLA --MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNA-SMLLRRPISI
PYRK_LACLM --MSQLQEMMTVVSQREVAYNIFEMVLKGTLVDEMDLPGQFLHLAVPNG-AMLLRRPISI
PYRK_STRPN ---------MKVVAQEEIAPAIFELVLEGEMVEAMR-AGQFLHLRVPDD-AHLLRRPISI
PYRK_FUSNN ----MKIEDCTVEENVQIAKDTYKMKIKGNFVKECRTPGQFVNIRIGDGREHVLRRPISI
A1ASB4_PELPD -----MQFTSMVLSNAEVSPGYHRMRLTAPPEFAAARAGQFVMVRVGGGIDPLLRRPFGI
B1I4M7_DESAP MDELTYVTDAKVVSHRRVAAGCRRLVLAAPEIARAVRPGQFLHVRCDGTADPLLRRPLSV
PYRK_PYRAB -----MLRRVMIKETWEVAKNVRAFRF--DEK-LDFIPGQFIMLWLPGINEKPFSLADKD
PYRK_PYRHO -----MLRRVTLKETWEVAKNIKAFRF--DEK-LDFTPGQFIMVWLPGVNEKPFSLADKD
PYRK_PYRFU -----MLRRVSIEETWEVAKNIKAFRL--SEK-LEFTPGQFIMLWLPGVEEKPLSLADKN
PYRK_METKA -MVSVKPIPAEVVENREECERTIVLRLRPERP-IRWEPGQFLMLGISGVDEKPMAFSGGD
PYRK_METAC ----MLPLNVTITQITEESPLVRTFFFDHRFE--DMDPGQFVMVWVRGVDEVPMGLS---
PYRK_METJA ---MEKPVICRIKEIIEESPTVKTFVVDKDF---DFKPGQFAMLWLPGVDEKPFGFS---
PYRK_METTH MDSMNVPEVLEIKRIVEESESVKTFIFSWDFR-REVRPGQFVMVWDFR-DEKPMSVSLID
PYRK_THEAC ------MNRITVDQVRDEAKNVRTLFFRWDH---DVKPGQFVMVWLPGLGEIPMSLSYVG
PYRK_THEVO ------MINLKIEENVKESQNVNTLYFNWDQ---DIRPGQFAMIWIPGYGEIPMSFSGLG
PYRK_ARCFU ------MYYTRITQIERLTDEVATLYFSISL---RSYPGQFVMVYVPGCEEIPLSLSSSN
Q3AC04_CARHZ ----MQDLKGLVVENIPITKEIYKLQVSVPEEILPEIVPGSFAMVKVEAKGVFLRRPFSF
B5YJH0_THEYD ---MNKLFKSKVISNEALTEEIYLISLEISDDVETK-PGQFCILRVNQRLDPLLGRPFSI
: : . : : .
PYRK_CLOAB -----------YDADDEKISFLYSVV--GKGTEILSKLKSGDEIKITGPLGNGFN--VKR
PYRK_CLOPE -----------CEVNGNDVRFVYATV--GAGTNEMKKMISGDEIEIIGPLGNGFD--INK
Q18CS7_CLOD6 -----------HDIDEEGITFLYKVV--GEGTQILSNLKVNDNIKLEGPYGNGY----AK
PYRK_CALS4 -----------NDFEEEKMTILYQVR--GEGTKNLSQMKEGDILEITGPHGNGFE--ILE
PYRK_BACCL ---------CHIDHKQGQCTIIYRQ--EGKGTALLAQKQPGDTVDVLGPLGNGFPLEAAP
PYRK_HALH5 ---------CHVDEQTSELTLLYRA--EGQGTKRLAQKARGETVDILGPLGQGFPLEAIA
PYRK_BACSU ---------ADVNFEKNEVTIIYRV--DGEGTRLLSLKQQGELVDVLGPLGNGFPVNEVQ
PYRK_LISIN ---------CSYDKTAKTCILLYRV--EGDGTKDFSSLSKGDSIDVLGPLGKGFDLNTIP
PYRK_LISMO ---------CSYDKTAKTCILLYRV--EGDGTRDFSKLSEGDTIDVLGPLGKGFDIDTTP
PYRK_LACLA ---------SSWDKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVV
PYRK_LACLM ---------SSWDKRAKTCTILYRIGDETTGTYKLSKLESGAKVDVMGPLGNGFPVAEVT
PYRK_STRPN ---------SSIDKANKQCHLIYRI--DGAGTAIFSTLSQGDTLDVMGPQGNGFDLSDLD
PYRK_FUSNN ---------SEIDRGENLVTIIYRI--VGEGTKFMANIKKGNEIDVMGPLGRGYDVLSLT
A1ASB4_PELPD FDLSTHTPLHDGAVSQPCFEMLYRV--VGKGTALLSTLHATDRLDVLGPLGTGFDLGTP-
B1I4M7_DESAP ---------HDADRERGTVTILYRV--VGRGTALLAQKKQGGRVNVLGPLGRGFDPPAE-
PYRK_PYRAB ---------------------LIVVKKVGPFTSKLFKLEEGDYVWIRGPYGNGFKSV---
PYRK_PYRHO ---------------------LIVVKRVGPFTSKLFTLEEGDYLWIRGPYGNGFKEV---
PYRK_PYRFU ---------------------LIMVKKVGRFTNELFKLKEGDYVWIRGPYGHGFSGK---
PYRK_METKA D-----------------REFELTIEIVGPFTERCADLEPGDVVWVRGPYGKPFEVR---
PYRK_METAC ------------------RNNSITVQKVGEATSKLFELKEGDSFGLRGPFGKGFTLPSR-
PYRK_METJA ------------------SKNSFSVARVGEFTKKMHELKEGDIIGVRGPYGTYFEP--I-
PYRK_METTH PV---------------RSEIGISIRRVGEFTDRVHGLSEGDLLGIRGPYGRGFEL--M-
PYRK_THEAC ------------------SPKGITVKAYGKVSQAMIDMEPGHEFYIRGPYGNGFQIE---
PYRK_THEVO ------------------RRKSITVKAYGSASRKLTELKAGDDLFLRGPYGNGFDVR---
PYRK_ARCFU ---------------------SVTVKAVGETTASLINAKEGQYVGVRGAFGSAFTPS---
Q3AC04_CARHZ -----------ADVDLKTGLVTFYIKTVGQGTGALRELPPGREISMLLPLGRGFTVMS--
B5YJH0_THEYD -----------FEHEKGEIKFLYRLK--GKGTNILTKLKKGDSITLTGPFGRWYPFP---
: . : . * :
PYRK_CLOAB ISGKVAIVCGGIGVAPMVYLAKNLKNCN----------VDFYAGFKTVSKTVDNVEKYVK
PYRK_CLOPE DYGRVALVSGGIGTAPMLELAKSLRKNNK------DIKMDFYGGFRDDIYLVDEIAEYVD
Q18CS7_CLOD6 VDGKVALVGGGIGVAPLYLVAKNIKNCD------------AYLGFREDVILEDEYKQVCN
PYRK_CALS4 GK-RVLIVGGGVGIAPLLYLAKKVKAQK----------LYIALGFKRETFLVEKFEG-LG
PYRK_BACCL AGSRALLVGGGIGVPPLYELAKQLTKR------GVKVVSVLGFQTKAAVFYEEEFAAFGE
PYRK_HALH5 SGETALLIGGGIGVPPLYYLAKRLKAK------GCHVINVLGFQSAKDSFYYEQFSQLGT
PYRK_BACSU PGKTALLVGGGVGVPPLQELSKRLIEK------GVNVIHVLGFQSAKDVFYEEECRQYGD
PYRK_LISIN APKTALLIGGGIGVPPMYQLGKELADK------GVQVTFVNGFQSEKDSFYEKEMTEYGT
PYRK_LISMO APKTALLIGGGIGVPPMYQLGKELAEK------GVQVMFVNGFQSAKDSFYAQEMAEYGT
PYRK_LACLA STDKILIVGGGIGVPPLYELAKQLEEK------NCQMTILLGFASEKVKILEKEFAELKN
PYRK_LACLM STDKILIIGGGIGVPPLYELAKQLEKT------GCQMTILLGFASENVKILENEFSNLKN
PYRK_STRPN EQNQVLLVGGGIGVPPLLEVAKELHER------GVKVVTVLGFANKDAVILKTELAQYGQ
PYRK_FUSNN KEQTALLVGGGIGVPPLYELAKQFNKR------GIKTIIILGFNSKDEVFYEDEFKKFGE
A1ASB4_PELPD -GAEKLLVGGGVGLAPLYLLARHLVQ-------QSPVRLFAGGRTRDDILCITEFERLGV
B1I4M7_DESAP -HRRVAVVGGGIGIAPLFFLARELSADPLKRVPRRAVTVFQGARTAAE-LDVADFTTLPV
PYRK_PYRAB -EGKVALVAGGIGIPPIYALAKYGNLE------EKVL--IYGARSKEELATL-DIENYVD
PYRK_PYRHO -KGKVALVAGGIGIPPIYALAKHGKLE------EKVL--IYGARGKDELALL-DIENYVD
PYRK_PYRFU -GKSVALIAGGIGIPPIYALAKYGNFK------RSIL--IYGARTKEEIALPKDIESYVD
PYRK_METKA -GSRAVVVAGGTGVAPLVPLVERLRRA------RVHVTSVLGGPHADRLPRKDDLEKLSD
PYRK_METAC -GEKVLLIAGGVGAAPLSPYAEAASAA------GAEVHTILGARSAGDLLFEWRFEALG-
PYRK_METJA -GDKVLAVAGGIGAAPIITAVEEFSKQ------GIEITTILGARTKEELLFLDRFEKVS-
PYRK_METTH -GRDILLVGGGIGMAPLAALADEATAR------GMRVDALVAARTADELLFLDRLEAAGV
PYRK_THEAC -SGRKLIIGGGSGIASLLPIADSDT------------DALISAKTKEELIFTDRFPESR-
PYRK_THEVO -EGRKLLVGGGSGIVSLYPIADQET------------DALISAKTRDELIFKDRFPESR-
PYRK_ARCFU --KRALIVAGGIGIAPMKYLYEYLMKC------GSKVSVVYGERTAKNLFWLDKFDRIT-
Q3AC04_CARHZ --GKSLLVAGGIGIAPLKFLAKEITKN--------GGEVRIIYGVKNAEMFIPEIVNAFE
B5YJH0_THEYD -EGDFIVIAGGIGLASVYYLIKKFPQR---------AYLFYGVRNEKEILFYEELKRLSK
: ** * .:
PYRK_CLOAB ELK-LSTEDGSIGHKGYVTDNFK------PEEYDYVLCCGPEIMMYKVVKMCEQKNV--P
PYRK_CLOPE EVK-ISTNTGKHGHKGFVTEILP------LQEYDTVLCCGPEIMMKKVVEMCKEAKV--N
Q18CS7_CLOD6 KVY-TTVGNT------FVTDIID------VEKYDYILTCGPTPMMEKLVKMVEGTKT--R
PYRK_CALS4 EVV-VTTEEGSTGRKGLVTSVVEE----MIGEVDIVYGCGPKPMLKALQEISMKANV--L
PYRK_BACCL TH--VATDDGSHGTAGRVTDVIEARSLE----FDVLYACGPKPMLRALAERFPN--R--P
PYRK_HALH5 TY--VATVDGTAGTKGFVTHVLNQEALS----YNVVYSCGPTPMLKAVSERFIG--E--R
PYRK_BACSU TY--VATADGSYGETGFVTDVIKRKKLE----FDILLSCGPTPMLKALKQEYAH--K--E
PYRK_LISIN VH--IATVDGSYGTQGFVTDITKNFPEE----PDVIYSCGPKAMLQAVKASFPE--T--K
PYRK_LISMO VH--IATVDGSLGTQGFVTDITKNFPEE----PDVIYSCGPKAMLQAVKASFPE--T--K
PYRK_LACLA VSLKIATDDGSYGTKGHVGMLMEEIDFE----VDALYTCGAPAMLKAVAKKYEQL-E--R
PYRK_LACLM VTLKIATDDGSYGTKGHVGMLMNEIDFE----VDALYTCGAPAMLKAVAKKYDQL-E--R
PYRK_STRPN VF--VTTDDGSYGIKGNVSVVINDLDSQ----FDAVYSCGAPGMMKYINQTFDDH-P--R
PYRK_FUSNN TY--VSTIDGSVGTKGFVTDVIKKLQAENNLVFDKYYSCGPVPMLKALVNAVGE-----D
A1ASB4_PELPD ECY-VATEDGSLGECGLVTEALVSRLEQL-EGGAELFACGPHPMLKAVAAIAAYHAI--P
B1I4M7_DESAP NLF-TATDDGSRGHAGSVVELFLDTVCH--EPVDWVSAAGPPGMLRALAGALETLGL--S
PYRK_PYRAB EVV-ITTDDGSAGIKGFPTDVLAR----RKVEFSQVYACGPEVMLAKVLEIMNYERT---
PYRK_PYRHO EIV-ITTDDGSYGIKGFPTDVLAK----RKEEFSQVYACGPEIMLAKVLEIMNYERT---
PYRK_PYRFU EVI-ITTDDGSYGIKGFPTDVLME----RRSEFDYVYACGPEIMLAKILEIMEFENV---
PYRK_METKA ELY-VTTEDGSEGRKGFPTDVLEEL--VEKECPDVVYACGPEGMLVRVAEIAREHDVP--
PYRK_METAC DIY-ASTDDGSKGVKGFVTDVLKG---LDVAAYDRIAVCGPEIMMASVFRLLEERKVLEK
PYRK_METJA RLE-ICTDDGSFGFKGFTTEKMKEV--LKEEKFDLIITCGPEIMMKKVVEIANEYNI--P
PYRK_METTH NIS-TCTDDGSCGFKGFAHERLLT----LEENHDMAAVCGPEPMMFQVMRILDERDV--P
PYRK_THEAC -LF-IATDDGSEGFHGFPHEFLDR---LDISVYRKIYVCGPEPMLYRVMQKLASMNA--R
PYRK_THEVO -RF-IATDDGSDGFHGFAHELLQR---INIDSYEAIYVCGPEQMMYKVLQVLKGRKV--F
PYRK_ARCFU ----VTTEDGSFGLKGTVLDALKL---EKLDEYEKIYVCGSEGMLRATYDFLKERDALDK
Q3AC04_CARHZ DVE-VYAEVSGLGKRGLVLDGLKST---DLSTYNQIYLCGPEAMLKAAKPVLQNYSG--L
B5YJH0_THEYD QLYISTEKETSYAYKGVITELFREK---SIQLPFPIYACGPMMMLKELKKIVNENRP---
.*. *:
PYRK_CLOAB VYISMEKKMACGIGACLVCTCKTKGGR------RRACKEGPVFLGSELILND--------
PYRK_CLOPE VYISMEKHMACGVGACLVCICKTKSGN------KRTCKDGPVFNGLEVEF----------
Q18CS7_CLOD6 IMVSLENHMACGVGACLVCTCKTNGGN------KKTCKDGPVFWGEDVIFNG--------
PYRK_CALS4 CQISLEEKMACGIGACLGCACKVREDKG--FSYKRVCRDGPVFWAEEVLF----------
PYRK_BACCL VYLSLEERMGCGVGACFACVCH-VPGSE--TAYKKVCSDGPVFRAGEVVL----------
PYRK_HALH5 AFISMEERMGCGIGACFACVCH-VTGDEAGTAYRKICTDGPVFPVGEVVL----------
PYRK_BACSU VYLSMEERMGCGIGACFACVCH-TNESE--TSYVKVCLDGPVFKAQEVAL----------
PYRK_LISIN TYLSLEERMACGIGACYACVCP-KAGDT--KKQFKVCEDGPVFRADEVSL----------
PYRK_LISMO TYLSLEERMACGIGACYACVCP-KADDT--NKQFKVCEDGPVFRADEVKL----------
PYRK_LACLA LYISMESRMACGIGACYACVEH-DKEDE--NHALKVCEDGPVFLGKQLLL----------
PYRK_LACLM LYISMESRMACGIGACYACVEH-DKEDE--SHALKVCEDGPVFLGKQLSL----------
PYRK_STRPN AYLSLESRMACGMGACYACVLK-VPENE--TVSQRVCEDGPVFRTGTVVL----------
PYRK_FUSNN GYISLENRMACGIGACYACVCK-KKKKD---DYTRVCYDGPVYLASDVEIE---------
A1ASB4_PELPD CQVSLEGYMACGVGACLGCVTPGHGHTAETPDYRCVCKEGPVFPAHELGWEE--------
B1I4M7_DESAP GEFSLEERMGCGIGACVCCSC--RIGAPDRWEYRRVCADGPVFGAREVVWE---------
PYRK_PYRAB -QISAERYMKCGIGICGSCALGP----------YLVCRDGPVFTGEQL-KGTEIGKFSRL
PYRK_PYRHO -QISAERYMKCGIGICGSCALGP----------YLVCRDGPVFTGEQL-KDTEFGKFTRL
PYRK_PYRFU -EVSAERYMKCGIGVCGSCALGP----------YLVCRDGPVFSGKQL-INTEFGKYSRT
PYRK_METKA CQVSVVRYVKCGEGICGSCALGKG---------LLVCRDGPVFWTEEL-EGTEFGGVRRD
PYRK_METAC AEFSLHRYFKCGIGVCGACCIDL--------SGLRVCKDGPVFSGIQL-LGSELGKYSRD
PYRK_METJA VQVSMERYMKCGIGICGQCCVDD--------EGLCVCKDGPVFWGDKLKFIREFGKYKRD
PYRK_METTH AQLSLERYMKCAVGICGQCCLDD--------TGFRVCAEGPVFWSQELSRVREFGRYRRD
PYRK_THEAC AEFSLERTMKCGIGICDSCSVG----------GLQVCRQGPVFDIEQLRNNPEFGISRTT
PYRK_THEVO VQFSLERTMKCGIGICDSCSLG----------GKQVCKEGPVFNIEELIGNPEFGVYRTT
PYRK_ARCFU AEFSLERYMRCGIGVCGSCVIEN---------GLRVCADGPVFNASELPW----------
Q3AC04_CARHZ IEVSLESFMACGFGACLGCAVKVFSNNE--FVYKKVCQDGPVFNFKEVVL----------
B5YJH0_THEYD CYVATEERMACGVGACLGCVIKTRED------FKRVCTEGPVFELKELVL----------
.: . *. * * * * :***: :
PYRK_CLOAB -----------
PYRK_CLOPE -----------
Q18CS7_CLOD6 -----------
PYRK_CALS4 -----------
PYRK_BACCL -----------
PYRK_HALH5 -----------
PYRK_BACSU -----------
PYRK_LISIN -----------
PYRK_LISMO -----------
PYRK_LACLA -----------
PYRK_LACLM -----------
PYRK_STRPN -----------
PYRK_FUSNN -----------
A1ASB4_PELPD -----------
B1I4M7_DESAP -----------
PYRK_PYRAB PDGRIKSLR--
PYRK_PYRHO PDGRIKGLR--
PYRK_PYRFU PDGRIKPL---
PYRK_METKA VTGKPE-----
PYRK_METAC ASGRRIKI---
PYRK_METJA ASGKKIYY---
PYRK_METTH PAGRRVPW---
PYRK_THEAC YSGKRVYLNMK
PYRK_THEVO YSGRRIRLNVK
PYRK_ARCFU -----------
Q3AC04_CARHZ -----------
B5YJH0_THEYD -----------