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Species code:	ANATD
Taxonomy:	Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales; Thermoanaerobacterales Family III. Incertae Sedis; Caldicellulosiruptor (TaxID: 521460) [NEWT/ NCBI]
Description:	Anaerocellum thermophilum (strain DSM 6725 / Z-1320) is a strictly anaerobic, asporogenous, Gram-positive bacterium isolated from a continental thermal spring in Kamchatka, Russia. It is a thermophile, growing optimally at 75 degrees Celsius, and utilizes a variety of polymeric carbohydrates as carbon and energy sources. These include crystalline cellulose, hemicellulose, pectin, starch, and gum Arabic. The organism grows rapidly, typically reaching cell densities above 108 cell/ml within 18 hours of growth at 75 degrees Celsius. It also grows on unprocessed plant biomass, including hardwood (poplar) and on grasses with low lignin (napier grass, bermuda grass) and high lignin (switchgrass) contents. Acetate, lactate, carbon dioxide and hydrogen are the predominant end products. A. thermophilum has several properties that make it of potential utility in biomass to biofuel conversion systems. It is the most thermophilic microorganism known to efficiently hydrolyze crystalline cellulose, it simultaneously utilizes cellulose and hemicellulose, which are the main components of plant biomass, it can degrade lignocellulosic biomass without chemical pretreatment, and it produces hydrogen gas as a main end product. (adapted from http://genome.jgi-psf.org/finished_microbes/anath/anath.home.html).
Properties:	Presence of flagella: Yes Human pathogen: No Interaction: No Number of membranes: 1 Number of inteins: 2 in 2 different sequences
Statistics:	Number of ANATD entries in the UniProt Knowledgebase: 2652 (210 in UniProtKB/Swiss-Prot + 2442 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number CP001393 (circular; 2,919,718 bp) (download entry) • Plasmid pATHE01 EMBL accession number CP001394 (circular; 8,291 bp) (download entry) • Plasmid pATHE02 EMBL accession number CP001395 (circular; 3,653 bp) (download entry)
Reference(s):	[1] Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kataeva I., Adams M.W.W. ; "Complete sequence of chromosome of Anaerocellum thermophilum DSM 6725."; Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. [2] Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kataeva I., Adams M.W.W. ; "Complete sequence of plasmid1 of Anaerocellum thermophilum DSM 6725."; Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. [3] Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kataeva I., Adams M.W.W. ; "Complete sequence of plasmid2 of Anaerocellum thermophilum DSM 6725."; Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
Web links:	Official genome site(s): http://genome.jgi-psf.org/finished_microbes/anath/anath.home.html Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=29407 Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/project.php?pid=29407 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Athe_DSM6725  EBI Proteome Analysis page

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