HAMAP: Corynebacterium diphtheriae complete proteome
General information

Species:  Corynebacterium diphtheriae
Species code: CORDI
Taxonomy: Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium (TaxID: 1717) [NEWT/ NCBI]
Description: Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods which include both pathogenic and non-pathogenic species that can live in a large variety of habitats. In addition to being animal and human pathogens, they have been isolated from soil, plant material, waste water, and dairy products.

C.diphtheriae produces the diphtheria toxin, which is usually encoded by a bacteriphage or by an integrated prophage as in this strain. Diphtheria is an acute disease that usually affects the tonsils, throat, nose and/or skin. It is passed from person to person by droplet transmission, usually by breathing in diphtheria bacteria after an infected person has coughed or sneezed. It can lead to breathing problems, heart failure, paralysis and sometimes death.
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 1
Number of inteins:0
Statistics: Number of CORDI entries in the UniProt Knowledgebase: 2264 (334 in UniProtKB/Swiss-Prot + 1930 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC 700971 / NCTC 13129 / Biotype gravis
Genome structure:
Chromosome EMBL accession number BX248353 (circular; 2,488,635 bp) (download entry)
Reference(s):
[1] MEDLINE=22965443; PubMed=14602910; [ NCBI , EBI , Israel , Japan ]
Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J. ;
"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.";
Nucleic Acids Res. 31:6516-6523(2003).
Web links:
Official genome site(s):
http://www.sanger.ac.uk/Projects/C_diphtheriae/
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Corynebacterium&GLspecies=diphtheriae&GLstrain=NCTC13129
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid257309%5Borgn%5D
GenoList: http://bioinfo.hku.hk/GenoList/index.pl?database=diphtelist
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cdip_NCTC13129
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntcd01
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Corynebacterium_diphtheriae.html
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p87_Cor_dipht
 EBI Proteome Analysis page



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