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Species code:	FRATN
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales; Francisellaceae; Francisella (TaxID: 401614) [NEWT/ NCBI]
Description:	Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. Tularemia can affect both humans and animals. The subspecies tularensis (Type A) and holarctica (Type B) are the ones most commonly associated with the human disease. During World War II, the use of F.tularensis as a biological weapon was studied by Japan, Soviet Union and USA. Strains of F. tularensis subsp. novicida are not considered virulent in humans, although they may cause disease in compromised individuals. They do however cause a disease in mice that is very similar to tularemia. Subspecies novicida belongs to a subspecies that diverged from a common ancestor before the divergence of the 2 human pathogenic subspecies tularensis and holarctica. This strain was isolated from water in Utah in 1950.
Properties:	Presence of flagella: No Human pathogen: Rarely Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of FRATN entries in the UniProt Knowledgebase: 1719 (275 in UniProtKB/Swiss-Prot + 1444 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number CP000439 (circular; 1,910,031 bp) (download entry)
Reference(s):	[1] PubMed=17550600; [ NCBI , EBI , Israel , Japan ] Rohmer L., Fong C., Abmayr S., Wasnick M., Larson Freeman T.J., Radey M., Guina T., Svensson K., Hayden H.S., Jacobs M., Gallagher L.A., Manoil C., Ernst R.K., Drees B., Buckley D., Haugen E., Bovee D., Zhou Y., Chang J., Levy R., Lim R., Gillett W., Guenthener D., Kang A., Shaffer S.A., Taylor G., Chen J., Gallis B., D'Argenio D.A., Forsman M., Olson M.V., Goodlett D.R., Kaul R., Miller S.I., Brittnacher M.J. ; "Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains."; Genome Biol. 8:R102.1-R102.16(2007).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid401614%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ftul_U112 PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p16088_Fra_tular  EBI Proteome Analysis page

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