Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP: Rickettsia rickettsii (strain Sheila Smith) complete proteome
General information

Species:  Rickettsia rickettsii (strain Sheila Smith)
Species code: RICRS
Taxonomy: Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group (TaxID: 392021) [NEWT/ NCBI]
Description: Rickettsia rickettsii is the causative agent of the Rocky Mountain spotted fever (RMSF) and is the prototype bacterium in the spotted fever group of rickettsiae. It is transmitted by hard ticks (Ixodidae). Rocky Mountain spotted fever is the most severe and most frequently reported rickettsial illness in the United States. It also occurs in Mexico and in Central and South America. The symptoms of the Rocky Mountain spotted fever may follow within one to fourteen days after the victim has been bitten. There is a high fever, with chills, muscle aches and a severe headache concentrated in the forehead area. Also, eyes may become red, muscles may feel weak and there may be body swelling. A rash also forms around the third to fifth day. RMSF affects about 800 people in the United States each year. Before anti-biotic treatment was available 20 to 30 percent of the cases were fatal. However, with the discovery of an antibiotic, the suffering and danger has decreased; it causes death in about 15 percent of its victims over age 70, and in only about two percent of infected victims under age 30. If an antibiotic is started rapidly, the mortality rate is ten percent.
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia (intracellular obligate)
Number of membranes: 2
Number of inteins:0
Statistics: Number of RICRS entries in the UniProt Knowledgebase: 1345 (232 in UniProtKB/Swiss-Prot + 1113 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    Sheila Smith
Genome structure:
Chromosome EMBL accession number CP000848 (linear; 1,257,710 bp) (download entry)
Reference(s):
[1] Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Dasch G., Eremeeva M. ;
"Complete genome sequence of Rickettsia rickettsii.";
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=9636
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Rric_Sheila_Smith
PATRIC: http://patric.vbi.vt.edu/organism/overview.php?organismId=3
 EBI Proteome Analysis page



Tools