HAMAP proteomes
Sulcia muelleri (strain GWSS)

General information

Species:  Sulcia muelleri (strain GWSS)
Species code: SULMW
Taxonomy: Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales; Candidatus Sulcia (TaxID: 444179) [NEWT/ NCBI]
Description: Sulcia muelleri, a member of the Bacteroidetes, is an ancient symbiont of a large group of sap-feeding insects that, in addition to Sulcia, have at least on other symbiont, for example Baumannia in the case of sharpshooters. Sulcia muelleri was isolated from Homalodisca vitripennis, the Glassy-Winged Sharpshooter. Its genome is 245530 base pairs in length with a GC content of 22.4 %. It encodes 228 protein genes, 31 tRNAs representing all 20 amino acids, one rRNA operon and one tmRNA. The coding density is 96.1 %. 33 % and 21.3 % of the protein-coding genes are devoted to translation-related and amino-acid synthesis functions, respectively.

Pathways for leucine, isoleucine, valine, threonine, phenylalanine and tryptophan are complete. Genes for DNA repair comprise only mutL and mutS. There are very few transporters and strikingly no transporter for amino acid has been found. Both the SecY and twin-arginine protein translocation systems are present. Sulcia muelleri seems to be able to synthesize NADH from NAD and to use it to generate ATP.

The metabolic capabilities of Baumannia and Sulcia are complementary in that Sulcia is primarily responsible for the amino acid biosynthesis whereas Baumannia is devoted to cofactor and vitamin synthesis. As an example of complementarity, Baumannia is able to make cysteine from homoserine but is unable to make homoserine whereas Sulcia is able to make homoserine from aspartate but is unable to make cysteine.
Properties: Presence of flagella: not known
Human pathogen: No
Interaction: Animal symbiont in Insecta
Number of membranes: 2
Statistics: Number of SULMW entries in UniProtKB: 228 (62 in UniProtKB/Swiss-Prot + 166 in UniProtKB/TrEMBL)

Genome(s) sequenced

Strain:    GWSS
Genome structure:
Chromosome EMBL accession number CP000770 (circular; 245,530 bp) (download entry)
Reference(s):
[1] Pubmed=18048332;
McCutcheon J.P., Moran N.A. ;
"Parallel genomic evolution and metabolic interdependence in an ancient symbiosis.";
Proc. Natl. Acad. Sci. U.S.A. 104:19392-19397(2007).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid444179%5Borgn%5D


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