AC   MF_00213;
DC   Protein; auto
TR   HAMAP; MF_00213; -; 1; level=0
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Names: HypA_HybF
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ID   HYPA
DE   RecName: Full=Hydrogenase maturation factor HypA;
GN   Name=hypA;
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CC   -!- FUNCTION: Involved in the maturation of [NiFe] hydrogenases. Required
CC       for nickel insertion into the metal center of the hydrogenase.
CC   -!- SIMILARITY: Belongs to the HypA/HybF family.
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DR   Pfam; PF01155; HypA; 1; trigger=no
DR   PIRSF; PIRSF004761; Hydrgn_mat_HypA; 1; trigger=no
DR   NCBIfam; TIGR00100; HypA; 1; trigger=no
DR   PROSITE; PS01249; HYPA; 1; trigger=no
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KW   Metal-binding
KW   Nickel
case <FTGroup:1>
KW   Zinc
end case
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GO   GO:0016151; F:nickel cation binding
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
GO   GO:0036211; P:protein modification process
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FT   From: HYPA_HELPY (P0A0U4)
FT   BINDING         2
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT   Condition: H
FT   BINDING         74
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         77
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: [CH]
FT   BINDING         91
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         94
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
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Size: 105-160;
Related: MF_02099!;
Template: P0A700; P0A703; P0A0U4; Q5JIH3;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in BRADU, ECOLI, SALTY, SYNY3
Plasmid: None
Comments: Some species such as E.coli have a HypA homolog, named HybF (see MF_02099).
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# Revision 1.26 2023/06/01
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