AC   MF_00250;
DC   Protein; auto
TR   HAMAP; MF_00250; -; 1; level=0
XX
Names: RNApol_arch_Rpo10
XX
ID   RPO10
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo10;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase subunit N;
GN   Name=rpo10; Synonyms=rpoN;
XX
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion.;
end case
CC   -!- SUBUNIT: Part of the RNA polymerase complex.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA
CC       polymerase subunit family.
XX
DR   Pfam; PF01194; RNA_pol_N; 1; trigger=no
DR   PROSITE; PS01112; RNA_POL_N_8KD; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Nucleotidyltransferase
KW   DNA-directed RNA polymerase
KW   Transcription
case <FTGroup:1>
KW   Zinc
KW   Metal-binding
end case
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity
GO   GO:0006351; P:DNA-templated transcription
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
XX
FT   From: RPO10_METTH (O26147)
FT   BINDING         6
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         9
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         43
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         44
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
XX
Size: 55-90;
Related: None;
Template: O26147; P39472; B8YB63; Q980Z8;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Archaeoglobus species have a slightly longer N-terminus.
XX
# Revision 1.27 2022/11/19
//