AC   MF_00551;
DC   Protein; auto
TR   HAMAP; MF_00551; -; 1; level=0
XX
Names: Uridine_kinase
XX
ID   URK
DE   RecName: Full=Uridine kinase;
DE            EC=2.7.1.48;
DE   AltName: Full=Cytidine monophosphokinase;
DE   AltName: Full=Uridine monophosphokinase;
GN   Name=udk;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + uridine = ADP + H(+) + UMP; Xref=Rhea:RHEA:16825,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16704, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:57865, ChEBI:CHEBI:456216; EC=2.7.1.48;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + cytidine = ADP + CMP + H(+); Xref=Rhea:RHEA:24674,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17562, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:60377, ChEBI:CHEBI:456216;
CC   -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage pathway;
CC       CTP from cytidine: step 1/3.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway;
CC       UMP from uridine: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the uridine kinase family.
XX
DR   Pfam; PF00485; PRK; 1; trigger=no
DR   PRINTS; PR00478; PHRIBLKINASE; 1; trigger=no
DR   PRINTS; PR00988; URIDINKINASE; 1; trigger=no
DR   NCBIfam; TIGR00235; Udk; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Kinase
KW   ATP-binding
KW   Nucleotide-binding
XX
GO   GO:0005524; F:ATP binding
GO   GO:0004849; F:uridine kinase activity
GO   GO:0008655; P:pyrimidine-containing compound salvage
GO   GO:0005737; C:cytoplasm
XX
FT   From: URK_ECOLI (P0A8F4)
FT   BINDING         15..22
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: G-[GA]-[ST]-[GAC]-[GSA]-G-K-[ST]
XX
Size: 205-225;
Related: None;
Template: P0A8F4;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.25 2023/06/01
//