AC   MF_00961;
DC   Protein; auto
TR   HAMAP; MF_00961; -; 1; level=0
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Names: Sigma70_RpoH
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ID   RPOH
DE   RecName: Full=RNA polymerase sigma factor RpoH;
DE   AltName: Full=RNA polymerase sigma-32 factor;
GN   Name=rpoH;
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CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is involved in regulation of expression of
CC       heat shock genes.
CC   -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoH subfamily.
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DR   PROSITE; PS00715; SIGMA70_1; 1; trigger=no
DR   PROSITE; PS00716; SIGMA70_2; 1; trigger=no
DR   Pfam; PF00140; Sigma70_r1_2; 0-1; trigger=no
DR   Pfam; PF04542; Sigma70_r2; 1; trigger=no
DR   Pfam; PF04545; Sigma70_r4; 1; trigger=no
DR   PRINTS; PR00046; SIGMA70FCT; 1; trigger=no
DR   NCBIfam; TIGR02392; rpoH_proteo; 1; trigger=no
DR   NCBIfam; TIGR02937; sigma70-ECF; 1; trigger=no
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KW   Cytoplasm
KW   DNA-binding
KW   Sigma factor
KW   Stress response
KW   Transcription
KW   Transcription regulation
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GO   GO:0003677; F:DNA binding
GO   GO:0016987; F:sigma factor activity
GO   GO:0010468; P:regulation of gene expression
GO   GO:0009408; P:response to heat
GO   GO:0006352; P:DNA-templated transcription initiation
GO   GO:0005737; C:cytoplasm
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FT   From: RPOH_ECOLI (P0AGB3)
FT   DNA_BIND        253..272
FT                   /note="H-T-H motif"
FT   REGION          53..122
FT                   /note="Sigma-70 factor domain-2"
FT   REGION          228..280
FT                   /note="Sigma-70 factor domain-4"
FT   MOTIF           77..80
FT                   /note="Interaction with polymerase core subunit RpoC"
FT   Condition: [DE]-[LVIM]-[IVM]-[QSA]
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Size: 250-406;
Related: None;
Template: P0AGB3;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.11 2023/06/01
//