AC   MF_01250;
DC   Protein; auto
TR   HAMAP; MF_01250; -; 1; level=0
XX
Names: Pyrophosphat_PpaX
XX
ID   PPAX
case <OC:Bacillales>
DE   RecName: Full=Pyrophosphatase PpaX;
DE            EC=3.6.1.1;
end case
case not <OC:Bacillales>
DE   RecName: Full=Putative pyrophosphatase PpaX;
DE            EC=3.6.1.1;
end case
GN   Name=ppaX;
XX
case <OC:Bacillales>
CC   -!- FUNCTION: Hydrolyzes pyrophosphate formed during P-Ser-HPr
CC       dephosphorylation by HPrK/P. Might play a role in controlling the
CC       intracellular pyrophosphate pool.
end case
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:43474; EC=3.6.1.1;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. PpaX family.
XX
DR   Pfam; PF00702; Hydrolase; 1; trigger=no
DR   PRINTS; PR00413; HADHALOGNASE; 1; trigger=no
DR   NCBIfam; TIGR01549; HAD-SF-IA-v1; 1; trigger=no
DR   NCBIfam; TIGR01509; HAD-SF-IA-v3; 1; trigger=no
DR   NCBIfam; TIGR02009; PGMB-YQAB-SF; 1; trigger=no
XX
KW   Hydrolase
KW   Magnesium
XX
GO   GO:0000287; F:magnesium ion binding
GO   GO:0004427; F:inorganic diphosphate phosphatase activity
XX
FT   From: PPAX_BACSU (Q9JMQ2)
FT   ACT_SITE        12
FT                   /note="Nucleophile"
FT   Condition: D
XX
Size: 214-220;
Related: None;
Template: Q9JMQ2;
Scope:
 Bacteria; Bacillales
 Bacteria; Clostridia
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: In Bacillales, the gene corresponding to this protein is located in the proximity
 of hprK gene which encodes HPr kinase/phosphorylase.
XX
# Revision 1.15 2023/06/01
//