AC   MF_01686;
DC   Protein; auto
TR   HAMAP; MF_01686; -; 1; level=0
XX
Names: Thymidy_synth_arch
XX
ID   TYSY
DE   RecName: Full=Putative thymidylate synthase;
DE            Short=TS;
DE            Short=TSase;
DE            EC=2.1.1.-;
GN   Name=thyA;
XX
CC   -!- FUNCTION: May catalyze the biosynthesis of dTMP using an unknown
CC       cosubstrate.
CC   -!- PATHWAY: Pyrimidine metabolism; dTTP biosynthesis.
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the thymidylate synthase family. Archaeal-type
CC       ThyA subfamily.
XX
DR   PROSITE; PS00091; THYMIDYLATE_SYNTHASE; 1; trigger=no
DR   Pfam; PF00303; Thymidylat_synt; 1; trigger=no
DR   PRINTS; PR00108; THYMDSNTHASE; 1; trigger=no
DR   NCBIfam; TIGR03283; Thy_syn_methano; 1; trigger=no
XX
KW   Cytoplasm
KW   Methyltransferase
KW   Nucleotide biosynthesis
KW   Transferase
XX
GO   GO:0004799; F:thymidylate synthase activity
GO   GO:0006231; P:dTMP biosynthetic process
GO   GO:0006235; P:dTTP biosynthetic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: TYSY_METTM (P80305)
FT   ACT_SITE        146
FT   Condition: C
XX
Size: 209-223;
Related: MF_00008;
Template: P80305;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Bacterial ThyA belong to a separate family (MF_00008).
XX
# Revision 1.8 2024/01/31
//