AC   MF_01856;
DC   Protein; auto
TR   HAMAP; MF_01856; -; 1; level=0
XX
Names: 16SrRNA_methyltr_B
XX
ID   RSMB
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase B;
DE            EC=2.1.1.176;
DE   AltName: Full=16S rRNA m5C967 methyltransferase;
DE   AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RsmB;
GN   Name=rsmB; Synonyms=sun;
XX
CC   -!- FUNCTION: Specifically methylates the cytosine at position 967 (m5C967)
CC       of 16S rRNA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-
CC         methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42748, Rhea:RHEA-COMP:10219, Rhea:RHEA-COMP:10220,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; EC=2.1.1.176;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family.
XX
DR   PROSITE; PS01153; NOL1_NOP2_SUN; 1; trigger=no
DR   Pfam; PF01189; Nol1_Nop2_Fmu; 1; trigger=no
DR   Pfam; PF01029; NusB; 1; trigger=no
DR   NCBIfam; TIGR00563; RsmB; 1; trigger=no
DR   PROSITE; PS01153; NOL1_NOP2_SUN; 1; trigger=no
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1; trigger=no
XX
KW   Cytoplasm
KW   Methyltransferase
KW   RNA-binding
KW   rRNA processing
KW   S-adenosyl-L-methionine
KW   Transferase
XX
GO   GO:0016434; F:rRNA (cytosine) methyltransferase activity
GO   GO:0031167; P:rRNA methylation
GO   GO:0005737; C:cytoplasm
XX
FT   From: RSMB_ECOLI (P36929)
FT   BINDING         254..260
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [ACSV]-[ACPS]-[AGP]-[PQ]-[AG]-[GINS]-K
FT   ACT_SITE        375
FT                   /note="Nucleophile"
FT   Condition: C
FT   BINDING         277
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
FT   BINDING         303
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
FT   BINDING         322
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
XX
Size: 422-433;
Related: None;
Template: P36929;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: The family is restricted to Enterobacterales in order to avoid wrong matches.
XX
# Revision 1.15 2023/06/01
//