AC   MF_01955;
DC   Protein; auto
TR   HAMAP; MF_01955; -; 1; level=0
XX
Names: Urease_beta_gamma
XX
ID   URE23
case <OC:Campylobacterales>
DE   RecName: Full=Urease subunit alpha;
DE            EC=3.5.1.5;
DE   AltName: Full=Urea amidohydrolase subunit alpha;
GN   Name=ureA;
else case not <OC:Campylobacterales>
DE   RecName: Full=Urease subunit gamma/beta;
DE            EC=3.5.1.5;
DE   AltName: Full=Urea amidohydrolase subunit gamma/beta;
GN   Name=ureAB;
end case
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1.
case <OC:Campylobacterales>
CC   -!- SUBUNIT: Heterohexamer of 3 UreA (alpha) and 3 UreB (beta) subunits.
else case not <OC:Campylobacterales>
CC   -!- SUBUNIT: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta)
CC       subunits.
end case
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the urease gamma
CC       subunit family.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the urease beta
CC       subunit family.
case <OC:Campylobacterales>
CC   -!- CAUTION: The orthologous protein is known as the gamma/beta subunit
CC       (UreAB) in most other bacteria.
end case
XX
DR   Pfam; PF00699; Urease_beta; 1; trigger=no
DR   Pfam; PF00547; Urease_gamma; 1; trigger=no
DR   NCBIfam; TIGR00192; Urease_beta; 1; trigger=no
DR   NCBIfam; TIGR00193; Urease_gam; 1; trigger=no
XX
KW   Cytoplasm
KW   Hydrolase
XX
GO   GO:0009039; F:urease activity
GO   GO:0019627; P:urea metabolic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: URE23_HELPY (P14916)
FT   REGION          Nter..102
FT                   /note="Urease gamma"
FT   REGION          103..Cter
FT                   /note="Urease beta"
XX
Size: 219-238;
Related: MF_00739; MF_01954;
Template: P14916;
Scope:
 Bacteria; Kitasatosporales
 Bacteria; Deinococcales
 Bacteria; Campylobacterales
 Bacteria; Pseudomonadaceae
 Archaea; Sulfolobales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.20 2023/06/01
//