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HAMAP annotation rule: MF_00134
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General rule information

Accession MF_00134
Dates 1-JUN-2001 (Created)
18-AUG-2011 (Last updated, Version 29)
Data class Protein

case <OC:Bacteria>
Predictors HAMAP; MF_00134_B; [distribution of match scores in UniProtKB];[seed alignment for MF_00134_B]
end case


case <OC:Archaea>
Predictors HAMAP; MF_00134_A; [distribution of match scores in UniProtKB];[seed alignment for MF_00134_A]
end case

Names IGPS


Propagated annotation

Identifier, protein and gene names
Identifier TRPC
Protein name
RecName: Full=Indole-3-glycerol phosphate synthase;
Short=IGPS;
EC=4.1.1.48;
Gene name trpC
Comments
CATALYTIC ACTIVITY: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.
SIMILARITY: Belongs to the TrpC family.
Cross-references
Pfam PF00218; IGPS; 1;
PROSITE PS00614; IGPS; 1;
Keywords
Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis, Lyase, Decarboxylase.
Gene Ontology
GO:0004425; Molecular function: indole-3-glycerol-phosphate synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.


Additional information


case <OC:Bacteria>
Size range: 250-305 amino acids
end case


case <OC:Archaea>
Size range: 226-274 amino acids
end case

Related UniRules: None
Template: Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SULSO): [Recover all]
Scope: Bacteria
Archaea
Fusion: Nter: None; Cter: MF_00135 (trpF), MF_00211 (trpD)
Duplicate: in NOSS1, ANAVT, PSEU2, STRCO
Plasmid encoded: None
Comments: Possible wrong start in PYRKO, SYNY3 and VIBPA

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UniProtKB rule member sequences