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| HAMAP annotation rule MF_00134 |
| Accession | MF_00134 |
| Dates | 1-JUN-2001 (Created) 18-AUG-2011 (Last updated, Version 29) |
| Name | IGPS |
| Scope | Bacteria Archaea |
case <OC:Bacteria>
| Triggered by |
end case
case <OC:Archaea>
| Triggered by |
end case
| Identifier |
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| Protein name |
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| Gene name |
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| CATALYTIC ACTIVITY | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O. |
| PATHWAY | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate; step 4/5. |
| SIMILARITY | Belongs to the TrpC family. |
Amino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
Lyase
Decarboxylase
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
Lyase
Decarboxylase
GO:0004425; Molecular function: indole-3-glycerol-phosphate synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.
GO:0000162; Biological process: tryptophan biosynthetic process.
case <OC:Bacteria>
| Size range: | 250-305 amino acids |
end case
case <OC:Archaea>
| Size range: | 226-274 amino acids |
end case
| Related Rules: | None |
| Templates: | Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SULSO): [Recover all] |
| Fusion: | Nter: None; Cter: MF_00135 (trpF), MF_00211 (trpD) |
| Comments: | Possible wrong start in PYRKO, SYNY3 and VIBPA |