HAMAP annotation rule MF_00134
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Accession MF_00134
Dates 1-JUN-2001 (Created)
18-AUG-2011 (Last updated, Version 29)
Name IGPS
Scope Bacteria
Archaea
case <OC:Bacteria>
end case

case <OC:Archaea>
end case




Identifier
TRPC
Protein name
RecName: Full=Indole-3-glycerol phosphate synthase;
Short=IGPS;
EC=4.1.1.48;
Gene name
trpC


CATALYTIC ACTIVITY 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
PATHWAY Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate; step 4/5.
SIMILARITY Belongs to the TrpC family.




GO:0004425; Molecular function: indole-3-glycerol-phosphate synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.


Pfam PF00218; IGPS; 1;
PROSITE PS00614; IGPS; 1;


case <OC:Bacteria>
Size range: 250-305 amino acids
end case
case <OC:Archaea>
Size range: 226-274 amino acids
end case
Related Rules: None
Templates: Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SULSO): [Recover all]
Fusion: Nter: None; Cter: MF_00135 (trpF), MF_00211 (trpD)
Comments: Possible wrong start in PYRKO, SYNY3 and VIBPA