AC   MF_00370;
DC   Protein; auto
TR   HAMAP; MF_00370; -; 1; level=0
XX
Names: Shik_kinase_arch
XX
ID   AROK
DE   RecName: Full=Shikimate kinase;
DE            Short=SK;
DE            EC=2.7.1.71;
GN   Name=aroK;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + shikimate = 3-phosphoshikimate + ADP + H(+);
CC         Xref=Rhea:RHEA:13121, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:36208, ChEBI:CHEBI:145989, ChEBI:CHEBI:456216;
CC         EC=2.7.1.71;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       5/7.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the GHMP kinase family. Archaeal shikimate
CC       kinase subfamily.
XX
DR   Pfam; PF08544; GHMP_kinases_C; 1; trigger=no
DR   Pfam; PF00288; GHMP_kinases_N; 1; trigger=no
DR   PIRSF; PIRSF005758; Shikimt_kin_arch; 1; trigger=no
DR   NCBIfam; TIGR01920; Shik_kin_archae; 1; trigger=no
DR   PROSITE; PS00627; GHMP_KINASES_ATP; 1; trigger=no
XX
KW   Cytoplasm
KW   Amino-acid biosynthesis
KW   Aromatic amino acid biosynthesis
KW   Transferase
KW   Kinase
KW   ATP-binding
KW   Nucleotide-binding
XX
GO   GO:0005524; F:ATP binding
GO   GO:0004765; F:shikimate kinase activity
GO   GO:0009073; P:aromatic amino acid family biosynthetic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: AROK_METJA (Q58835)
FT   BINDING         86..96
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: P-x(3)-G-L-x-[GS]-S-[SA]-A
XX
Size: 268-294;
Related: None;
Template: Q58835;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Bacterial aroK belong to a separate family
XX
# Revision 1.33 2023/06/01
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