AC   MF_00475;
DC   Protein; auto
TR   HAMAP; MF_00475; -; 1; level=0
XX
Names: Trp_repressor
XX
ID   TRPR
case <OC:Enterobacterales>
DE   RecName: Full=Trp operon repressor;
else
DE   RecName: Full=Trp operon repressor homolog;
end case
GN   Name=trpR;
XX
case <OC:Enterobacterales>
CC   -!- FUNCTION: This protein is an aporepressor. When complexed with L-
CC       tryptophan it binds the operator region of the trp operon (5'-
CC       ACTAGT-'3') and prevents the initiation of transcription. The complex
CC       also regulates trp repressor biosynthesis by binding to its regulatory
CC       region.
else
CC   -!- FUNCTION: This protein is an aporepressor. When complexed with L-
CC       tryptophan it binds the operator region of the trp operon and prevents
CC       the initiation of transcription.
end case
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the TrpR family.
XX
DR   Pfam; PF01371; Trp_repressor; 1; trigger=no
DR   NCBIfam; TIGR01321; TrpR; 1; trigger=no
XX
KW   Cytoplasm
KW   Transcription
KW   Transcription regulation
KW   Repressor
KW   DNA-binding
XX
GO   GO:0003677; F:DNA binding
GO   GO:0045892; P:negative regulation of DNA-templated transcription
GO   GO:0005737; C:cytoplasm
XX
FT   From: TRPR_ECOLI (P0A881)
FT   DNA_BIND        68..91
XX
Size: 92-125;
Related: None;
Template: P0A881;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.30 2023/06/01
//