AC   MF_00638;
DC   Protein; auto
TR   HAMAP; MF_00638; -; 1; level=0
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Names: Anti_sigma_B
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ID   RSBW
DE   RecName: Full=Serine-protein kinase RsbW;
DE            EC=2.7.11.1;
DE   AltName: Full=Anti-sigma-B factor;
DE   AltName: Full=Sigma-B negative effector RsbW;
GN   Name=rsbW;
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CC   -!- FUNCTION: Negative regulator of sigma-B activity. Phosphorylates and
CC       inactivates its specific antagonist protein, RsbV. Upon phosphorylation
CC       of RsbV, RsbW is released and binds to sigma-B, thereby blocking its
CC       ability to form an RNA polymerase holoenzyme (E-sigma-B).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1;
CC   -!- SIMILARITY: Belongs to the anti-sigma-factor family.
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DR   Pfam; PF02518; HATPase_c; 1; trigger=no
DR   NCBIfam; TIGR01924; rsbW_low_gc; 1; trigger=no
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KW   ATP-binding
KW   Kinase
KW   Nucleotide-binding
KW   Serine/threonine-protein kinase
KW   Transferase
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GO   GO:0004672; F:protein kinase activity
GO   GO:0010468; P:regulation of gene expression
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FT   None
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Size: 157-162;
Related: MF_00637;
Template: P17904;
Scope:
 Bacteria; Bacillales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.19 2023/06/01
//