AC   MF_01242;
DC   Protein; auto
TR   HAMAP; MF_01242; -; 1; level=0
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Names: Aliphatic_amidase
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ID   AMIE
DE   RecName: Full=Aliphatic amidase;
DE            EC=3.5.1.4;
DE   AltName: Full=Acylamide amidohydrolase;
GN   Name=amiE;
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CC   -!- FUNCTION: Catalyzes the hydrolysis of short-chain aliphatic amides to
CC       their corresponding organic acids with release of ammonia.
CC   -!- FUNCTION: Also exhibits in vitro acyl transferase activity,
CC       transferring the acyl moiety of short-chain amides to hydroxylamine to
CC       form hydroxamates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a monocarboxylic acid amide + H2O = a monocarboxylate +
CC         NH4(+); Xref=Rhea:RHEA:12020, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:35757, ChEBI:CHEBI:83628; EC=3.5.1.4;
CC   -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC       Aliphatic amidase family.
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DR   Pfam; PF00795; CN_hydrolase; 1; trigger=no
DR   PROSITE; PS50263; CN_HYDROLASE; 1; trigger=yes
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KW   Hydrolase
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GO   GO:0004040; F:amidase activity
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FT   From: AMIE_PSEAE (P11436)
FT   ACT_SITE        59
FT                   /note="Proton acceptor"
FT   Condition: E
FT   ACT_SITE        134
FT                   /note="Proton donor"
FT   Condition: K
FT   ACT_SITE        166
FT                   /note="Nucleophile"
FT   Condition: C
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Size: 339-348;
Related: MF_01243;
Template: Q9L543; Q9RQ17; O25067; P11436; Q01360;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.18 2019/11/19
//