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HAMAP annotation rule: MF_01306
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General rule information

Accession MF_01306
Dates 3-DEC-2002 (Created)
9-FEB-2012 (Last updated, Version 28)
Data class Protein

case <OC:Bacteria> or <OG:Chloroplast>
Predictors HAMAP; MF_01306_B; [distribution of match scores in UniProtKB];[seed alignment for MF_01306_B]
end case


case <OC:Archaea>
Predictors HAMAP; MF_01306_A; [distribution of match scores in UniProtKB];[seed alignment for MF_01306_A]
end case

Names Ribosomal_S4


Propagated annotation

Identifier, protein and gene names

case <OC:Bacteria> and not <OC:Cyanobacteria>
Identifier RS4
Protein name
RecName: Full=30S ribosomal protein S4;
Gene name rpsD

else case <OC:Cyanobacteria>
Identifier RS4
Protein name
RecName: Full=30S ribosomal protein S4;
Gene name rpsD, rps4

else case <OC:Archaea>
Identifier RS4
Protein name
RecName: Full=30S ribosomal protein S4P;
Gene name rps4p

else case <OG:Chloroplast>
Identifier RR4
Protein name
RecName: Full=30S ribosomal protein S4, chloroplastic;
Gene name rps4
end case

Comments
FUNCTION: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity).
FUNCTION: With S5 and S12 plays an important role in translational accuracy (By similarity).
SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity (By similarity).

case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the ribosomal protein S4P family.
Cross-references
Pfam PF00163; Ribosomal_S4; 1;
PF01479; S4; 1;
TIGRFAMs TIGR01018; RpsD_arch; 1;
TIGR01017; RpsD_bact; 1;
PROSITE PS00632; RIBOSOMAL_S4; 1;
PS50889; S4; 1; trigger=PRU00182;
Keywords
Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding.
Gene Ontology
GO:0019843; Molecular function: rRNA binding.
GO:0006412; Biological process: translation.

case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case



Additional information


case <OC:Bacteria>
Size range: 192-257 amino acids
end case


case <OC:Archaea>
Size range: 159-219 amino acids
end case

Related UniRules: None
Template: P81288 (RS4_GEOSE); P21466 (RS4_BACSU); P0A7V8 (RS4_ECOLI); O54297 (RS4_SALTY); P80373 (RS4_THET8); P48270 (RR4_CHLRE): [Recover all]
Scope: Bacteria
Archaea
Plastid
Fusion: Nter: None; Cter: None
Duplicate: in ALKMQ, ALKOO, AZOSB, BDEBA, CLOAB, CLOB1, CLOBH, CLOBL, CLONN, CLOP1, CLOPE, CLOPS, LEPBL, METFK, NITEU, MYXXD, PSYIN, SYMTH
Plasmid encoded: None
Comments: Some plastid-encoded rps4 sequences (EIMTE, HELSJ, STIHE, TOXGO), as well as CARRP and NEOSM are quite divergent and thus have been made atypical. The second and third copies in the Clostridia have also been made atypical. In AZOSB the second copy is truncated and probably not functional.

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UniProtKB rule member sequences