HAMAP rule MF_01494
General rule information
[?]
Accession | MF_01494 |
Dates | 17-JUN-2014 (Created)
13-JAN-2023 (Last updated, Version 7) |
Name | DEAD_helicase_CshB |
Scope(s) |
Bacteria Bacillota |
Template(s) | P54475 (CSHB_BACSU); Q818H2 (CSHB_BACCR); Q8Y755 (CSHB_LISMO); [ Recover all ] |
Triggered by |
HAMAP; MF_01494 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | CSHB |
RecName: Full=DEAD-box ATP-dependent RNA helicase CshB;<br /> EC=<a href="https://enzyme.expasy.org/EC/3.6.4.13">3.6.4.13</a>; | |
Gene name | Name=cshB; |
Comments
[?]
FUNCTION | Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. |
CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the DEAD box helicase family. CshB subfamily. |
Keywords
[?]
ATP-binding | |
Cytoplasm | |
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a> | |
Hydrolase | |
Nucleotide-binding | |
RNA-binding | |
Stress response |
Gene Ontology
[?]
GO:0005524; Molecular function:ATP binding |
GO:0003724; Molecular function:RNA helicase activity |
GO:0003723; Molecular function:RNA binding |
GO:0006401; Biological process:RNA catabolic process |
GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
PROSITE | PS51194; HELICASE_CTER; 1; |
PROSITE | PS51195; Q_MOTIF; 1; |
Pfam | PF00270; DEAD; 1; |
Pfam | PF00271; Helicase_C; 1; |
Features
[?]
Additional information
[?]
Size range | 425-465 amino acids |
Related rules |
MF_01493 |
Fusion | Nter: None Cter: None |