HAMAP

Accession	MF_01691
Dates	30-APR-2009 (Created) 17-FEB-2010 (Last updated, Version 6)

Data class

Protein

Predictors

HAMAP; MF_01691; [distribution of match scores in UniProtKB];[seed alignment for MF_01691]

Names

DapH

Identifier

DAPH

Protein name

RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; EC=2.3.1.89; AltName: Full=Tetrahydrodipicolinate N-acetyltransferase; Short=THP acetyltransferase; Short=Tetrahydropicolinate acetylase;

Gene name

dapH

FUNCTION: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate (By similarity).

CATALYTIC ACTIVITY: Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + L-2-acetamido-6-oxoheptanedioate.

PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3.

SIMILARITY: Belongs to the transferase hexapeptide repeat family. DapH subfamily.

PROSITE	PS00101; HEXAPEP_TRANSFERASES; 1;
Pfam	PF08503; DapD_N; 1; PF00132; Hexapep; 4;

Acyltransferase, Amino-acid biosynthesis, Diaminopimelate biosynthesis, Lysine biosynthesis, Repeat, Transferase.

GO:0016407; Molecular function: acetyltransferase activity.
GO:0009089; Biological process: lysine biosynthetic process via diaminopimelate.
GO:0019877; Biological process: diaminopimelate biosynthetic process.

Size range:	228-257 amino acids
Related UniRules:	None
Template:	O34981 (DAPH_BACSU)
Scope:	Bacteria; Firmicutes Bacteria; Thermotogae Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None