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HAMAP rule MF_01725

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General rule information [?]

Accession MF_01725
Dates 26-FEB-2007 (Created)
26-JAN-2023 (Last updated, Version 26)
Name ABC_ATPase_ZnuC
Scope(s) Bacteria
Pseudomonadota
Template(s) P0A9X1 (ZNUC_ECOLI); [ Recover all ]
Triggered by PROSITE; PS51298 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ZNUC
Protein name RecName: Full=Zinc import ATP-binding protein ZnuC;
                 EC=7.2.2.20;
Gene name Name=znuC;

Comments [?]

FUNCTIONPart of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in); Xref=Rhea:RHEA:29795, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.2.2.20;
SUBUNITThe complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
Zinc transport
Ion transport
Zinc

Gene Ontology [?]

GO:0006829; Biological process:zinc ion transport
GO:0015633; Molecular function:ABC-type zinc transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]


Additional information [?]

Size range 250-300 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



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