HAMAP

Accession	MF_02012
Dates	27-JUN-2008 (Created) 5-DEC-2011 (Last updated, Version 6)

Data class

Protein

Predictors

HAMAP; MF_02012; [distribution of match scores in UniProtKB];[seed alignment for MF_02012]

Names

ZapA_type1

Identifier

ZAPA

Protein name

RecName: Full=Cell division protein ZapA; AltName: Full=Z ring-associated protein ZapA;

Gene name

zapA

FUNCTION: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity).

SUBUNIT: Homodimer. Interacts with FtsZ (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=Localizes at mid-cell (By similarity).

SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.

Pfam	PF05164; ZapA; 1;
General	Coiled_coil; -; 1-unlimited; trigger=Yes;

Cell cycle, Cell division, Coiled coil, Cytoplasm, Septation.

GO:0005886; Cellular component: plasma membrane.
GO:0000917; Biological process: barrier septum assembly.
GO:0051301; Biological process: cell division.

Size range:	104-109 amino acids
Related UniRules:	None
Template:	P0ADS2 (ZAPA_ECOLI); Q9HTW3 (ZAPA_PSEAE): [Recover all]
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Due to the high divergence of ZapA sequences, this family includes mostly members from the enterobacteria. There is a 3D-structure available for ZapA from Pseudomonas aeruginosa; this protein is not a member of this family though it probably has the same function; the information derived from the structure was included in this rule.