HAMAP

Accession	MF_02108
Dates	5-OCT-2009 (Created) 13-SEP-2010 (Last updated, Version 4)

Data class

Protein

Predictors

HAMAP; MF_02108; [distribution of match scores in UniProtKB];[seed alignment for MF_02108]

Names

HTH-type_MurR

Identifier

MURR

Protein name

RecName: Full=HTH-type transcriptional regulator murR; AltName: Full=MurPQ operon repressor;

Gene name

murR

FUNCTION: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer that weakens binding of murR to the operator (By similarity).

PATHWAY: Amino-sugar metabolism; N-acetylmuramate degradation [regulation].

SUBUNIT: Homotetramer (By similarity).

PROSITE	PS51071; HTH_RPIR; 1; trigger=PRU00390; PS51464; SIS; 1; trigger=PRU00797;
Pfam	PF01418; HTH_6; 1; PF01380; SIS; 1;

Carbohydrate metabolism, DNA-binding, Repressor, Transcription, Transcription regulation.

GO:0003700; Molecular function: sequence-specific DNA binding transcription factor activity.
GO:0043470; Biological process: regulation of carbohydrate catabolic process.
GO:0045892; Biological process: negative regulation of transcription, DNA-dependent.

Size range:	266-287 amino acids
Related UniRules:	None
Template:	P77245 (MURR_ECOLI)
Scope:	Bacteria; Enterobacteriales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None