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HAMAP rule MF_03135

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General rule information [?]

Accession MF_03135
Dates 22-OCT-2010 (Created)
1-JUN-2023 (Last updated, Version 6)
Name EF_Ts_euk
Scope(s) Eukaryota
Template(s) P43897 (EFTS_HUMAN); [ Recover all ]
Triggered by
case c? <OC:Eukaryota>
HAMAP; MF_00050 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier EFTS
Protein name RecName: Full=Elongation factor Ts, mitochondrial;
                 Short=EF-Ts;
                 Short=EF-TsMt;
case <OC:Vertebrata> or <OC:Amoebozoa>
Gene name Name=TSFM;
else case <OC:Caenorhabditis>
Gene name Name=tsfm-1;
else case <OC:Viridiplantae>
Gene name Name=EFTS;
else case <OC:Fungi>
Gene name Name=TSF1;
end case

Comments [?]

FUNCTIONAssociates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
SUBCELLULAR LOCATIONMitochondrion.
case not <AnyFeature:TransitM>
MISCELLANEOUSThis protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
SIMILARITYBelongs to the EF-Ts family.

Keywords [?]


Gene Ontology [?]

GO:0003746; Molecular function:translation elongation factor activity
GO:0006414; Biological process:translational elongation
GO:0005739; Cellular component:mitochondrion

Cross-references [?]

Pfam PF00889; EF_TS; 1-2;
Pfam PF00627; UBA; 1;
NCBIfam TIGR00116; Tsf; 1;
PROSITE PS01126; EF_TS_1; 1;
PROSITE PS01127; EF_TS_2; 1;
General TransitM; -; 0-1;

Features [?]


Additional information [?]

Size range 208-446 amino acids
Related rules None
Fusion Nter: None Cter: None



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