HAMAP proteomes
Aeromonas salmonicida (strain A449)

General information

Species:  Aeromonas salmonicida (strain A449)
Species code: AERS4
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales; Aeromonadaceae; Aeromonas (TaxID: 382245) [NEWT/ NCBI]
Description: Aeromonas salmonicida has been recognized as a pathogen of fish for over 100 years. In 1894 Emmerich and Weibel made the first report of its isolation during a disease outbreak at a Bavarian brown trout hatchery. The manifestations of the disease include furuncle-like swelling and, at a later stage, ulcerative lesions on infected trout. Since that time a number of subspecies of Aeromonas salmonicida have been recognized, although the taxonomy of the species is far from settled. While Aeromonas salmonicida was traditionally thought of as a pathogen of salmonids, global reports now confirm that this pathogen has been associated with clinical or covert disease in a variety of salmonid and non-salmonid species in freshwater, brackish water and sea water.

Aeromonas salmonicida (strain A449) was isolated from a brown trout in the Eure River, France in 1975 and harbors one chromosome and 5 plasmids. Comparison to the related A.hydrophilia ATCC 7966 (AERHH) show the presence of numerous insertion sequence, some of which are still active and various other mobile elements lreading to substantial genome rearrangements. A.salmonicida is no longer mobile and has also recently lost a type IV and type VI secretion systems, thus probably avoiding the host immune system. It seems to be undergoing genome decay and adaptation to its specific host (adapted from PMID 18801193).
Properties: Presence of flagella: No
Human pathogen: No
Interaction: Animal pathogen in Fish
Number of membranes: 2

Genome(s) sequenced

Strain:    A449
Genome structure:
• Chromosome EMBL accession number CP000644 (circular; 4,702,402 bp) (download entry)
• Plasmid pAsa1 EMBL accession number AY301063 (circular; 5,424 bp) (download entry)
• Plasmid pAsa2 EMBL accession number AY301064 (circular; 5,247 bp) (download entry)
• Plasmid pAsa3 EMBL accession number AY301065 (circular; 5,616 bp) (download entry)
• Plasmid pAsa4 EMBL accession number CP000645 (circular; 166,749 bp) (download entry)
• Plasmid pAsa5 EMBL accession number CP000646 (circular; 155,098 bp) (download entry)
[1] Pubmed=18801193;
Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C., Brown L.L. ;
"The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen.";
BMC Genomics 9:427-427(2008).
[2] Pubmed=12932739;
Boyd J., Williams J., Curtis B., Kozera C., Singh R., Reith M. ;
"Three small, cryptic plasmids from Aeromonas salmonicida subsp. salmonicida A449.";
Plasmid 50:131-144(2003).
Web links:
Official genome site(s):
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid382245%5Borgn%5D
GOLD: http://genomesonline.org/cgi-bin/GOLD/bin/GOLDCards.cgi?goldstamp=Gc00536