AC   MF_00004;
DC   Protein; auto
TR   HAMAP; MF_00004; -; 1; level=0
XX
Names: Aden_phosphoribosyltr
XX
ID   APT
DE   RecName: Full=Adenine phosphoribosyltransferase;
DE            Short=APRT;
DE            EC=2.4.2.7;
GN   Name=apt;
XX
CC   -!- FUNCTION: Catalyzes a salvage reaction resulting in the formation of
CC       AMP, that is energically less costly than de novo synthesis.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate +
CC         adenine; Xref=Rhea:RHEA:16609, ChEBI:CHEBI:16708, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:58017, ChEBI:CHEBI:456215; EC=2.4.2.7;
CC   -!- PATHWAY: Purine metabolism; AMP biosynthesis via salvage pathway; AMP
CC       from adenine: step 1/1.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family.
XX
DR   Pfam; PF00156; Pribosyltran; 1; trigger=no
DR   NCBIfam; TIGR01090; apt; 1; trigger=no
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Glycosyltransferase
KW   Purine salvage
XX
GO   GO:0003999; F:adenine phosphoribosyltransferase activity
GO   GO:0006168; P:adenine salvage
GO   GO:0009116; P:nucleoside metabolic process
GO   GO:0005737; C:cytoplasm
XX
FT   None
XX
Size: 150-280;
Related: None;
Template: P69503;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in METM5, METM7, METMP, METVS, RHIEC
Plasmid: in RHIEC
Comments: None
XX
# Revision 1.31 2023/06/01
//