AC   MF_00056;
DC   Protein; auto
TR   HAMAP; MF_00056; -; 1; level=0
XX
Names: KDO8P_synth
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ID   KDSA
DE   RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase;
DE            EC=2.5.1.55;
DE   AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase;
DE   AltName: Full=KDO-8-phosphate synthase;
DE            Short=KDO 8-P synthase;
DE            Short=KDOPS;
DE   AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase;
GN   Name=kdsA;
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CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-arabinose 5-phosphate + phosphoenolpyruvate + H2O = 3-deoxy-
CC         alpha-D-manno-2-octulosonate-8-phosphate + phosphate;
CC         Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985; EC=2.5.1.55;
CC   -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC       biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate:
CC       step 2/3.
case defined <Property:Membrane> and <Property:Membrane=2>
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
end case
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family. KdsA
CC       subfamily.
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DR   Pfam; PF00793; DAHP_synth_1; 1; trigger=no
DR   NCBIfam; TIGR01362; KDO8P_synth; 1; trigger=no
DR   PROSITE; PS52061; DAHPS_I; 1; trigger=yes
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KW   Cytoplasm
KW   Lipopolysaccharide biosynthesis
KW   Transferase
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GO   GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity
GO   GO:0009103; P:lipopolysaccharide biosynthetic process
GO   GO:0019294; P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
GO   GO:0005737; C:cytoplasm
XX
FT   None
XX
Size: 263-290;
Related: None;
Template: P0A715; O66496;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in BURPS, PSEPK
Plasmid: None
Comments: None
XX
# Version: 24
# Last updated date: 2025-04-15
# Created date: 2005-02-28
//