AC   MF_00065;
DC   Protein; auto
TR   HAMAP; MF_00065; -; 1; level=0
XX
Names: Adenylyl_sulf_kinase
XX
ID   CYSC
DE   RecName: Full=Adenylyl-sulfate kinase;
DE            EC=2.7.1.25;
DE   AltName: Full=APS kinase;
DE   AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
DE   AltName: Full=Adenosine-5'-phosphosulfate kinase;
GN   Name=cysC;
XX
CC   -!- FUNCTION: Catalyzes the synthesis of activated sulfate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate
CC         + ADP + H(+); Xref=Rhea:RHEA:24152, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58243, ChEBI:CHEBI:58339,
CC         ChEBI:CHEBI:456216; EC=2.7.1.25;
CC   -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from
CC       sulfate: step 2/3.
CC   -!- SIMILARITY: Belongs to the APS kinase family.
XX
DR   Pfam; PF01583; APS_kinase; 1; trigger=no
DR   NCBIfam; TIGR00455; ApsK; 1; trigger=no
XX
KW   Transferase
KW   Kinase
KW   ATP-binding
KW   Nucleotide-binding
KW   Phosphoprotein
XX
GO   GO:0004020; F:adenylylsulfate kinase activity
GO   GO:0005524; F:ATP binding
GO   GO:0000103; P:sulfate assimilation
XX
FT   From: CYSC_ECOLI (P0A6J1)
FT   BINDING         35..42
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: G-x(4)-G-K-[ST]
FT   ACT_SITE        109
FT                   /note="Phosphoserine intermediate"
FT   Condition: S
XX
Size: 155-214;
Related: None;
Template: P0A6J1;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: MF_00062 (cysN); MF_00066 (sat)
 Cter: None
Duplicate: in BACSU
Plasmid: in AZOBR, RHIME
Comments: Problematic entry
XX
# Revision 1.36 2023/06/01
//