AC MF_00072; DC Protein; auto TR HAMAP; MF_00072; -; 1; level=0 XX Names: Rel_fac_3 XX ID RF3 DE RecName: Full=Peptide chain release factor 3; DE Short=RF-3; GN Name=prfC; XX CC -!- FUNCTION: Increases the formation of ribosomal termination complexes CC and stimulates activities of RF-1 and RF-2. It binds guanine CC nucleotides and has strong preference for UGA stop codons. It may CC interact directly with the ribosome. The stimulation of RF-1 and RF-2 CC is significantly reduced by GTP and GDP, but not by GMP. CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase CC superfamily. Classic translation factor GTPase family. PrfC subfamily. XX DR Pfam; PF00009; GTP_EFTU; 1; trigger=no DR Pfam; PF03144; GTP_EFTU_D2; 1; trigger=no DR NCBIfam; TIGR00503; PrfC; 1; trigger=no DR PROSITE; PS00301; G_TR_1; 1; trigger=no DR PROSITE; PS51722; G_TR_2; 1; trigger=no XX KW Cytoplasm KW Protein biosynthesis KW GTP-binding KW Nucleotide-binding XX GO GO:0005525; F:GTP binding GO GO:0016149; F:translation release factor activity, codon specific GO GO:0006449; P:regulation of translational termination GO GO:0005737; C:cytoplasm XX FT From: RF3_ECOLI (P0A7I4) FT BINDING 20..27 FT /ligand="GTP" FT /ligand_id="ChEBI:CHEBI:37565" FT Condition: S-H-P-D-A-G-K-T FT BINDING 88..92 FT /ligand="GTP" FT /ligand_id="ChEBI:CHEBI:37565" FT Condition: D-T-P-G-H FT BINDING 142..145 FT /ligand="GTP" FT /ligand_id="ChEBI:CHEBI:37565" FT Condition: N-K-[LMYCVF]-D XX Size: 510-556; Related: None; Template: P0A7I4; Scope: Bacteria Fusion: Nter: None Cter: None Duplicate: None Plasmid: in RALN1 Comments: None XX # Revision 1.35 2023/11/28 //