AC MF_00101; DC Protein; auto TR HAMAP; MF_00101; -; 1; level=0 XX Names: AcpS XX ID ACPS DE RecName: Full=Holo-[acyl-carrier-protein] synthase; DE Short=Holo-ACP synthase; DE EC=2.7.8.7; DE AltName: Full=4'-phosphopantetheinyl transferase AcpS; GN Name=acpS; XX CC -!- FUNCTION: Transfers the 4'-phosphopantetheine moiety from coenzyme A to CC a Ser of acyl-carrier-protein. CC -!- CATALYTIC ACTIVITY: CC Reaction=apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo- CC [ACP]; Xref=Rhea:RHEA:12068, Rhea:RHEA-COMP:9685, Rhea:RHEA- CC COMP:9690, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:57287, CC ChEBI:CHEBI:58343, ChEBI:CHEBI:64479; EC=2.7.8.7; case or CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; end case CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the P-Pant transferase superfamily. AcpS family. XX DR Pfam; PF01648; ACPS; 1; trigger=no DR NCBIfam; TIGR00516; AcpS; 1; trigger=no DR NCBIfam; TIGR00556; Pantethn_trn; 1; trigger=no XX KW Cytoplasm KW Fatty acid biosynthesis KW Fatty acid metabolism KW Lipid biosynthesis KW Lipid metabolism case or KW Magnesium KW Metal-binding end case KW Transferase XX GO GO:0008897; F:holo-[acyl-carrier-protein] synthase activity case or GO GO:0000287; F:magnesium ion binding end case GO GO:0006633; P:fatty acid biosynthetic process GO GO:0005737; C:cytoplasm XX FT From: ACPS_ECOLI (P24224) FT BINDING 9 FT /ligand="Mg(2+)" FT /ligand_id="ChEBI:CHEBI:18420" FT Condition: [DE] FT BINDING 58 FT /ligand="Mg(2+)" FT /ligand_id="ChEBI:CHEBI:18420" FT Condition: [EQ] XX Size: 108-157; Related: None; Template: P96618; P24224; P0A2W6; Scope: Bacteria Fusion: Nter: None Cter: None Duplicate: in ECO57 Plasmid: None Comments: Possible wrong C-terminal sequence in THEMA; not shown in alignment and not used in size range XX # Revision 1.38 2023/06/01 //