AC   MF_00115;
DC   Protein; auto
TR   HAMAP; MF_00115; -; 1; level=0
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Names: MscL
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ID   MSCL
DE   RecName: Full=Large-conductance mechanosensitive channel;
GN   Name=mscL;
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CC   -!- FUNCTION: Channel that opens in response to stretch forces in the
CC       membrane lipid bilayer. May participate in the regulation of osmotic
CC       pressure changes within the cell.
CC   -!- SUBUNIT: Homopentamer.
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
else
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the MscL family.
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DR   Pfam; PF01741; MscL; 1; trigger=no
DR   NCBIfam; TIGR00220; MscL; 1; trigger=no
DR   PROSITE; PS01327; MSCL; 1; trigger=no
DR   General; Transmembrane; -; 2-3; trigger=yes
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case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Ion channel
KW   Ion transport
KW   Membrane
KW   Transmembrane
KW   Transport
KW   Transmembrane helix
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GO   GO:0008381; F:mechanosensitive monoatomic ion channel activity
GO   GO:0034220; P:monoatomic ion transmembrane transport
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 100-220;
Related: None;
Template: P0A742; P9WJN5; P68806; P94585; O68284; P44789; P68805;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in RHILO
Plasmid: None
Comments: None.
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# Revision 1.48 2023/06/01
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