AC   MF_00120;
DC   Protein; auto
c?   <OC:Bacteria> or <OC:Archaea>
TR   HAMAP; MF_00120; -; 1; level=0
XX
Names: GatA
XX
ID   GATA
DE   RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A;
DE            Short=Glu-ADT subunit A;
DE            EC=6.3.5.7;
GN   Name=gatA;
XX
CC   -!- FUNCTION: Allows the formation of correctly charged Gln-tRNA(Gln)
CC       through the transamidation of misacylated Glu-tRNA(Gln) in organisms
CC       which lack glutaminyl-tRNA synthetase. The reaction takes place in the
CC       presence of glutamine and ATP through an activated gamma-phospho-Glu-
CC       tRNA(Gln).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) +
CC         L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate;
CC         Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359,
CC         ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216; EC=6.3.5.7;
CC   -!- SUBUNIT: Heterotrimer of A, B and C subunits.
CC   -!- SIMILARITY: Belongs to the amidase family. GatA subfamily.
XX
DR   Pfam; PF01425; Amidase; 1; trigger=no
DR   NCBIfam; TIGR00132; GatA; 1; trigger=no
DR   PROSITE; PS00571; AMIDASES; 1; trigger=no
XX
KW   ATP-binding
KW   Ligase
KW   Nucleotide-binding
KW   Protein biosynthesis
XX
GO   GO:0050567; F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
GO   GO:0006412; P:translation
XX
FT   From: GATA_BACSU (O06491)
FT   ACT_SITE        79
FT                   /note="Charge relay system"
FT   Condition: K
FT   ACT_SITE        154
FT                   /note="Charge relay system"
FT   Condition: S
FT   ACT_SITE        178
FT                   /note="Acyl-ester intermediate"
FT   Condition: S
XX
Size: 423-524;
Related: None;
Template: O06491; Q9LCX3;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in CLOAB
Plasmid: None
Comments: There is a possible divergent gatA in ARCFU: AF1954
XX
# Revision 1.21 2023/06/01
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