AC   MF_00150;
DC   Protein; auto
TR   HAMAP; MF_00150; -; 1; level=0
XX
Names: ArgC_type1
XX
ID   ARGC
DE   RecName: Full=N-acetyl-gamma-glutamyl-phosphate reductase;
DE            Short=AGPR;
DE            EC=1.2.1.38;
DE   AltName: Full=N-acetyl-glutamate semialdehyde dehydrogenase;
DE            Short=NAGSA dehydrogenase;
GN   Name=argC;
XX
CC   -!- FUNCTION: Catalyzes the NADPH-dependent reduction of N-acetyl-5-
CC       glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate =
CC         H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH; Xref=Rhea:RHEA:21588,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29123, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:57936, ChEBI:CHEBI:58349; EC=1.2.1.38;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-
CC       L-ornithine from L-glutamate: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the NAGSA dehydrogenase family. Type 1
CC       subfamily.
XX
DR   Pfam; PF01118; Semialdhyde_dh; 1; trigger=no
DR   PROSITE; PS01224; ARGC; 1; trigger=no
DR   NCBIfam; TIGR01850; argC; 1; trigger=no
XX
KW   Cytoplasm
KW   Amino-acid biosynthesis
KW   Arginine biosynthesis
KW   Oxidoreductase
KW   NADP
XX
GO   GO:0003942; F:N-acetyl-gamma-glutamyl-phosphate reductase activity
GO   GO:0006526; P:arginine biosynthetic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: ARGC_ECOLI (P11446)
FT   ACT_SITE        154
FT   Condition: C
XX
Size: 308-364;
Related: MF_02083!;
Template: P11446;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in LACPL
Plasmid: None
Comments: See MF_01110 for ArgC type 2 subfamily. MF_00150 also matches LysY, which is a
 subfamily of ArgC type 1. MF_02083 is a child of MF_00150 and is specific for LysY.
XX
# Revision 1.44 2023/06/01
//