AC   MF_00170;
DC   Protein; auto
TR   HAMAP; MF_00170; -; 1; level=0
XX
Names: Rib_5P_isom_A
XX
ID   RPIA
DE   RecName: Full=Ribose-5-phosphate isomerase A;
DE            EC=5.3.1.6;
DE   AltName: Full=Phosphoriboisomerase A;
DE            Short=PRI;
GN   Name=rpiA;
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CC   -!- FUNCTION: Catalyzes the reversible conversion of ribose-5-phosphate to
CC       ribulose 5-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate;
CC         Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273;
CC         EC=5.3.1.6;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribose
CC       5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step
CC       1/1.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
XX
DR   Pfam; PF00455; DeoRC; 0-1; trigger=no
DR   Pfam; PF06026; Rib_5-P_isom_A; 1; trigger=no
DR   NCBIfam; TIGR00021; RpiA; 1; trigger=no
XX
KW   Isomerase
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GO   GO:0004751; F:ribose-5-phosphate isomerase activity
GO   GO:0009052; P:pentose-phosphate shunt, non-oxidative branch
XX
FT   From: RPIA_ECOLI (P0A7Z0)
FT   BINDING         28..31
FT                   /ligand="substrate"
FT   Condition: x-G-x-T
FT   BINDING         81..84
FT                   /ligand="substrate"
FT   Condition: D-x-x-D
FT   BINDING         94..97
FT                   /ligand="substrate"
FT   Condition: K-G-x-G
FT   ACT_SITE        103
FT                   /note="Proton acceptor"
FT   Condition: E
FT   BINDING         121
FT                   /ligand="substrate"
FT   Condition: [KR]
XX
Size: 215-262;
Related: None;
Template: P0A7Z0; O50083; Q72J47; Q58998;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in OCEIH, YERPE
Plasmid: None
Comments: None
XX
# Revision 1.25 2023/06/01
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