AC   MF_00175;
DC   Protein; auto
TR   HAMAP; MF_00175; -; 1; level=0
XX
Names: ClpX
XX
ID   CLPX
DE   RecName: Full=ATP-dependent Clp protease ATP-binding subunit ClpX;
GN   Name=clpX;
XX
CC   -!- FUNCTION: ATP-dependent specificity component of the Clp protease. It
CC       directs the protease to specific substrates. Can perform chaperone
CC       functions in the absence of ClpP.
CC   -!- SUBUNIT: Component of the ClpX-ClpP complex. Forms a hexameric ring
CC       that, in the presence of ATP, binds to fourteen ClpP subunits assembled
CC       into a disk-like structure with a central cavity, resembling the
CC       structure of eukaryotic proteasomes.
CC   -!- SIMILARITY: Belongs to the ClpX chaperone family.
XX
DR   Pfam; PF00004; AAA; 1; trigger=no
DR   Pfam; PF06689; zf-C4_ClpX; 1; trigger=no
DR   NCBIfam; TIGR00382; clpX; 1; trigger=no
DR   PROSITE; PS51902; CLPX_ZB; 1; trigger=yes
XX
KW   ATP-binding
KW   Chaperone
KW   Metal-binding
KW   Nucleotide-binding
KW   Zinc
XX
GO   GO:0005524; F:ATP binding
GO   GO:0051082; F:unfolded protein binding
GO   GO:0006457; P:protein folding
XX
FT   From: CLPX_ECOLI (P0A6H1)
FT   BINDING         120..127
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: [PS]-[ST]-G-x-G-K-T-[LYFV]
FT   BINDING         15
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         18
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         37
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         40
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
XX
Size: 380-500;
Related: MF_00249;
Template: P0A6H1; O25926;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in METCA, WOLSU
Plasmid: None
Comments: Unknown insert in BIFLO
XX
# Revision 1.28 2023/06/01
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