AC   MF_00187;
DC   Protein; auto
TR   HAMAP; MF_00187; -; 1; level=0
XX
Names: FdhD
XX
ID   FDHD
case <FTTag:persulfide>
DE   RecName: Full=Sulfur carrier protein FdhD;
else
DE   RecName: Full=Protein FdhD;
end case
GN   Name=fdhD;
XX
case <FTTag:persulfide>
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC       sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
else
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity.
end case
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the FdhD family.
XX
DR   Pfam; PF02634; FdhD-NarQ; 1; trigger=no
DR   NCBIfam; TIGR00129; fdhD_narQ; 1; trigger=no
DR   PIRSF; PIRSF015626; FdhD; 1; trigger=no
XX
KW   Cytoplasm
KW   Molybdenum cofactor biosynthesis
XX
GO   GO:0005737; C:cytoplasm
case <FTTag:persulfide>
GO   GO:0097163; F:sulfur carrier activity
end case
GO   GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process
XX
FT   From: FDHD_ECOLI (P32177)
FT   BINDING         260..265
FT                   /ligand="Mo-bis(molybdopterin guanine dinucleotide)"
FT                   /ligand_id="ChEBI:CHEBI:60539"
FT   Optional; Condition: F-x-[KR]-x-x-[KR]
FT   ACT_SITE        121
FT                   /note="Cysteine persulfide intermediate"
FT   Tag: persulfide; Condition: C
XX
Size: 220-340;
Related: None;
Template: P32177;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: In some species, the catalytic cysteine loop is missing. In these species,
 FdhD may function as a chaperone involved in FDH maturation. See PubMed=25649206.
XX
# Revision 1.27 2023/06/01
//