AC   MF_00247;
DC   Protein; auto
TR   HAMAP; MF_00247; -; 1; level=0
XX
Names: SthA
XX
ID   STHA
DE   RecName: Full=Soluble pyridine nucleotide transhydrogenase;
DE            Short=STH;
DE            EC=1.6.1.1;
DE   AltName: Full=NAD(P)(+) transhydrogenase [B-specific];
case <OC:Enterobacteriaceae>
GN   Name=sthA; Synonyms=udhA;
end case
case not <OC:Enterobacteriaceae>
GN   Name=sthA;
end case
XX
CC   -!- FUNCTION: Conversion of NADPH, generated by peripheral catabolic
CC       pathways, to NADH, which can enter the respiratory chain for energy
CC       generation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=NAD(+) + NADPH = NADH + NADP(+); Xref=Rhea:RHEA:11692,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57783, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:58349; EC=1.6.1.1;
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC       Note=Binds 1 FAD per subunit.;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class-I pyridine nucleotide-disulfide
CC       oxidoreductase family.
XX
DR   Pfam; PF00070; Pyr_redox; 1; trigger=no
DR   Pfam; PF07992; Pyr_redox_2; 1; trigger=no
DR   Pfam; PF02852; Pyr_redox_dim; 1; trigger=no
DR   PRINTS; PR00368; FADPNR; 1; trigger=no
DR   PRINTS; PR00945; HGRDTASE; 1; trigger=no
XX
KW   Cytoplasm
KW   Oxidoreductase
KW   Flavoprotein
KW   FAD
KW   NADP
KW   NAD
XX
GO   GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity
GO   GO:0006739; P:NADP metabolic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: STHA_ECOLI (P27306)
FT   BINDING         36..45
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
XX
Size: 463-471;
Related: None;
Template: P27306;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.31 2022/11/19
//