AC   MF_00285;
DC   Protein; auto
TR   HAMAP; MF_00285; -; 1; level=0
XX
Names: KdpB
XX
ID   KDPB
DE   RecName: Full=Potassium-transporting ATPase ATP-binding subunit;
DE            EC=7.2.2.6;
DE   AltName: Full=ATP phosphohydrolase [potassium-transporting] B chain;
DE   AltName: Full=Potassium-binding and translocating subunit B;
DE   AltName: Full=Potassium-translocating ATPase B chain;
GN   Name=kdpB;
XX
CC   -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport (or
CC       Kdp) system, which catalyzes the hydrolysis of ATP coupled with the
CC       electrogenic transport of potassium into the cytoplasm. This subunit is
CC       responsible for energy coupling to the transport system and for the
CC       release of the potassium ions to the cytoplasm.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate;
CC         Xref=Rhea:RHEA:16777, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29103, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216; EC=7.2.2.6;
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16778;
CC   -!- SUBUNIT: The system is composed of three essential subunits: KdpA, KdpB
CC       and KdpC.
case defined <Property:Membrane> and <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
else
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC       family. Type IA subfamily.
XX
DR   Pfam; PF00122; E1-E2_ATPase; 1; trigger=no
DR   Pfam; PF00702; Hydrolase; 1; trigger=no
DR   PRINTS; PR00119; CATATPASE; 1; trigger=no
DR   PRINTS; PR00120; HATPASE; 1; trigger=no
DR   NCBIfam; TIGR01494; ATPase_P-type; 1; trigger=no
DR   NCBIfam; TIGR01497; KdpB; 1; trigger=no
DR   PROSITE; PS00154; ATPASE_E1_E2; 1; trigger=no
DR   General; Transmembrane; -; 7; trigger=yes
XX
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Translocase
KW   Transport
KW   Ion transport
KW   Potassium
KW   Potassium transport
KW   Membrane
KW   Transmembrane
KW   Phosphoprotein
KW   Magnesium
KW   Metal-binding
KW   ATP-binding
KW   Nucleotide-binding
KW   Transmembrane helix
XX
GO   GO:0005524; F:ATP binding
GO   GO:0000287; F:magnesium ion binding
GO   GO:0008556; F:P-type potassium transmembrane transporter activity
GO   GO:0006813; P:potassium ion transport
GO   GO:0005886; C:plasma membrane
XX
FT   From: KDPB_ECOLI (P03960)
FT   BINDING         377..384
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: F-x-[AS]-x-[TS]-[RK]-x-S
FT   ACT_SITE        307
FT                   /note="4-aspartylphosphate intermediate"
FT   Condition: D
FT   BINDING         518
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         522
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         344
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: D
FT   BINDING         348
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: E
FT   BINDING         395
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: K
XX
Size: 620-760;
Related: None;
Template: P03960;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in NOSS1, LISIN, STAAM, STAAN
Plasmid: in DEIRA, HALSA, LISIN, RHIME
Comments: The S.typhi ortholog has a 112 amino acid internal deletion and is not
 used in the alignments.
XX
# Revision 1.65 2023/06/01
//