AC   MF_00320;
DC   Protein; auto
TR   HAMAP; MF_00320; -; 1; level=0
XX
Names: RNApol_arch_Rpo3
XX
ID   RPO3
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo3;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase subunit D;
GN   Name=rpo3; Synonyms=rpoD;
XX
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC       Note=Binds 1 [3Fe-4S] cluster.;
end case
CC   -!- SUBUNIT: Part of the RNA polymerase complex.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase
CC       subunit family.
XX
DR   PROSITE; PS00446; RNA_POL_D_30KD; 1; trigger=no
DR   PROSITE; PS00198; 4FE4S_FER_1; 0-1; trigger=no
DR   PROSITE; PS51379; 4FE4S_FER_2; 0-1; trigger=no
DR   Pfam; PF01000; RNA_pol_A_bac; 1; trigger=no
DR   Pfam; PF01193; RNA_pol_L; 1; trigger=no
XX
KW   Cytoplasm
KW   DNA-directed RNA polymerase
case <FTGroup:1>
KW   3Fe-4S
KW   Iron
KW   Iron-sulfur
KW   Metal-binding
end case
KW   Nucleotidyltransferase
KW   Transcription
KW   Transferase
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0003677; F:DNA binding
GO   GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity
case <FTGroup:1>
GO   GO:0051536; F:iron-sulfur cluster binding
end case
GO   GO:0006351; P:DNA-templated transcription
XX
FT   From: RPO3_SACS2 (P95989)
FT   BINDING         203
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT   Optional; Group: 1; Condition: C
FT   BINDING         206
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT   Optional; Group: 1; Condition: C
FT   BINDING         209
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT   Optional; Group: 1; Condition: C
XX
Size: 191-305;
Related: None;
Template: P95989; B8YB56; P39471; Q5JJF4;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.31 2022/11/19
//