AC   MF_00356;
DC   Protein; auto
TR   HAMAP; MF_00356; -; 1; level=0
XX
Names: DNApol_PolC
XX
ID   DPO3
DE   RecName: Full=DNA polymerase III PolC-type;
DE            Short=PolIII;
DE            EC=2.7.7.7;
GN   Name=polC;
XX
CC   -!- FUNCTION: Required for replicative DNA synthesis. This DNA polymerase
CC       also exhibits 3' to 5' exonuclease activity.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-C family. PolC
CC       subfamily.
XX
DR   Pfam; PF07733; DNA_pol3_alpha; 1; trigger=no
DR   Pfam; PF00929; RNase_T; 1; trigger=no
DR   Pfam; PF02811; PHP; 1; trigger=no
DR   Pfam; PF01336; tRNA_anti; 1; trigger=no
DR   NCBIfam; TIGR00573; Dnaq; 1; trigger=no
DR   NCBIfam; TIGR01405; PolC_Gram_pos; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Nucleotidyltransferase
KW   DNA-directed DNA polymerase
KW   DNA replication
KW   Hydrolase
KW   Nuclease
KW   Exonuclease
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GO   GO:0008408; F:3'-5' exonuclease activity
GO   GO:0003677; F:DNA binding
GO   GO:0003887; F:DNA-directed DNA polymerase activity
GO   GO:0006261; P:DNA-templated DNA replication
GO   GO:0005737; C:cytoplasm
XX
FT   None
XX
Size: 1367-1638;
Related: None;
Template: P13267; P47729; P0C1P9; Q2G1Z8;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: LACLA has a weird insertion not found in other polC.
XX
# Revision 1.32 2023/06/01
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