AC   MF_00393;
DC   Protein; auto
TR   HAMAP; MF_00393; -; 1; level=0
XX
Names: Glyc3P_acyltrans
XX
ID   PLSB
DE   RecName: Full=Glycerol-3-phosphate acyltransferase;
DE            Short=GPAT;
DE            EC=2.3.1.15;
GN   Name=plsB;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-
CC         phosphate + CoA; Xref=Rhea:RHEA:15325, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57597, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342; EC=2.3.1.15;
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-
CC       diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein;
CC       Cytoplasmic side.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein;
CC       Cytoplasmic side.
end case
CC   -!- DOMAIN: The HXXXXD motif is essential for acyltransferase activity and
CC       may constitute the binding site for the phosphate moiety of the
CC       glycerol-3-phosphate.
CC   -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
XX
DR   Pfam; PF01553; Acyltransferase; 1; trigger=no
DR   NCBIfam; TIGR03703; plsB; 1; trigger=no
XX
KW   Acyltransferase
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Membrane
KW   Phospholipid biosynthesis
KW   Phospholipid metabolism
KW   Transferase
XX
GO   GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity
GO   GO:0008654; P:phospholipid biosynthetic process
GO   GO:0005886; C:plasma membrane
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FT   From: PLSB_ECOLI (P0A7A7)
FT   MOTIF           305..310
FT                   /note="HXXXXD motif"
XX
Size: 775-886;
Related: None;
Template: P0A7A7;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Possible wrong start in XANAC, XANCP and XYLFA.
 Second divergent plsB in MYCTU; not shown in alignment.
XX
# Revision 1.32 2023/06/01
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