AC MF_00406; DC Protein; auto TR HAMAP; MF_00406; -; 1; level=0 XX Names: FabZ XX ID FABZ DE RecName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; DE EC=4.2.1.59; DE AltName: Full=(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; DE Short=(3R)-hydroxymyristoyl-ACP dehydrase; DE AltName: Full=Beta-hydroxyacyl-ACP dehydratase; GN Name=fabZ; XX CC -!- FUNCTION: Involved in unsaturated fatty acids biosynthesis. Catalyzes CC the dehydration of short chain beta-hydroxyacyl-ACPs and long chain CC saturated and unsaturated beta-hydroxyacyl-ACPs. CC -!- CATALYTIC ACTIVITY: CC Reaction=a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O; CC Xref=Rhea:RHEA:13097, Rhea:RHEA-COMP:9925, Rhea:RHEA-COMP:9945, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:78784, ChEBI:CHEBI:78827; EC=4.2.1.59; case or CC -!- SUBUNIT: Oligomer. end case CC -!- SUBCELLULAR LOCATION: Cytoplasm. case or CC -!- PTM: The N-terminus is blocked. end case CC -!- SIMILARITY: Belongs to the thioester dehydratase family. FabZ CC subfamily. XX DR Pfam; PF07977; FabA; 1; trigger=no DR NCBIfam; TIGR01750; FabZ; 1; trigger=no XX KW Cytoplasm KW Lyase KW Lipid A biosynthesis KW Lipid biosynthesis KW Lipid metabolism XX GO GO:0016836; F:hydro-lyase activity GO GO:0006633; P:fatty acid biosynthetic process GO GO:0009245; P:lipid A biosynthetic process GO GO:0005737; C:cytoplasm XX FT From: FABZ_ECOLI (P0A6Q6) FT ACT_SITE 54 FT Condition: H XX Size: 132-181; Related: MF_00405; Template: P0A6Q6; Scope: Bacteria Fusion: Nter: MF_00388 (lpxC) Cter: None Duplicate: in LACLA Plasmid: None Comments: Possible wrong start in SYNY3 XX # Revision 1.31 2023/06/01 //