AC   MF_00429;
DC   Protein; auto
TR   HAMAP; MF_00429; -; 1; level=0
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Names: NqrE
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ID   NQRE
DE   RecName: Full=Na(+)-translocating NADH-quinone reductase subunit E;
DE            Short=Na(+)-NQR subunit E;
DE            Short=Na(+)-translocating NQR subunit E;
DE            EC=7.2.1.1;
DE   AltName: Full=NQR complex subunit E;
DE   AltName: Full=NQR-1 subunit E;
GN   Name=nqrE;
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CC   -!- FUNCTION: NQR complex catalyzes the reduction of ubiquinone-1 to
CC       ubiquinol by two successive reactions, coupled with the transport of
CC       Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are
CC       probably involved in the second step, the conversion of ubisemiquinone
CC       to ubiquinol.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n
CC         Na(+)(out) + NAD(+); Xref=Rhea:RHEA:47748, Rhea:RHEA-COMP:9565,
CC         Rhea:RHEA-COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389,
CC         ChEBI:CHEBI:17976, ChEBI:CHEBI:29101, ChEBI:CHEBI:57540,
CC         ChEBI:CHEBI:57945; EC=7.2.1.1;
CC   -!- SUBUNIT: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and
CC       NqrF.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the NqrDE/RnfAE family.
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DR   Pfam; PF02508; Rnf-Nqr; 1; trigger=no
DR   PIRSF; PIRSF006102; NQR_DE; 1; trigger=no
DR   NCBIfam; TIGR01940; NqrE; 1; trigger=no
DR   General; Transmembrane; -; 6; trigger=yes
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KW   Translocase
KW   NAD
KW   Ubiquinone
KW   Transport
KW   Ion transport
KW   Sodium
KW   Sodium transport
KW   Cell membrane
KW   Membrane
KW   Transmembrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Transmembrane helix
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GO   GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO   GO:0006814; P:sodium ion transport
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 197-264;
Related: MF_00428;
Template: Q56589; A5F5Y5;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.41 2023/06/01
//