AC   MF_00543;
DC   Protein; auto
TR   HAMAP; MF_00543; -; 1; level=0
XX
Names: Tyr_phenol_lyase
XX
ID   TPL
DE   RecName: Full=Tyrosine phenol-lyase;
DE            EC=4.1.99.2;
DE   AltName: Full=Beta-tyrosinase;
GN   Name=tpl;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-tyrosine = NH4(+) + phenol + pyruvate;
CC         Xref=Rhea:RHEA:21704, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15882, ChEBI:CHEBI:28938, ChEBI:CHEBI:58315; EC=4.1.99.2;
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
XX
DR   Pfam; PF01212; Beta_elim_lyase; 1; trigger=no
DR   PIRSF; PIRSF001386; Trpase; 1; trigger=no
DR   NCBIfam; TIGR02618; Tyr_phenol_ly; 1; trigger=no
DR   PROSITE; PS00853; BETA_ELIM_LYASE; 1; trigger=no
XX
KW   Lyase
KW   Pyridoxal phosphate
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GO   GO:0050371; F:tyrosine phenol-lyase activity
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FT   From: TPL_CITFR (P31013)
FT   MOD_RES         257
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT   Condition: K
XX
Size: 456-473;
Related: MF_00544;
Template: P31013;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.24 2023/06/01
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