AC   MF_00549;
DC   Protein; auto
TR   HAMAP; MF_00549; -; 1; level=0
XX
Names: Methylglyoxal_synth
XX
ID   MGSA
DE   RecName: Full=Methylglyoxal synthase;
DE            Short=MGS;
DE            EC=4.2.3.3;
GN   Name=mgsA;
XX
CC   -!- FUNCTION: Catalyzes the formation of methylglyoxal from
CC       dihydroxyacetone phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=dihydroxyacetone phosphate = methylglyoxal + phosphate;
CC         Xref=Rhea:RHEA:17937, ChEBI:CHEBI:17158, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57642; EC=4.2.3.3;
CC   -!- SIMILARITY: Belongs to the methylglyoxal synthase family.
XX
DR   Pfam; PF02142; MGS; 1; trigger=no
DR   NCBIfam; TIGR00160; MGSA; 1; trigger=no
DR   PIRSF; PIRSF006614; Methylglyox_syn; 1; trigger=no
DR   PROSITE; PS01335; METHYLGLYOXAL_SYNTH; 1; trigger=no
DR   PROSITE; PS51855; MGS; 1; trigger=yes
XX
KW   Lyase
XX
GO   GO:0008929; F:methylglyoxal synthase activity
GO   GO:0019242; P:methylglyoxal biosynthetic process
XX
FT   From: MGSA_ECOLI (P0A731)
FT   BINDING         45..48
FT                   /ligand="substrate"
FT   Optional; Condition: T-G-[TAS]-T
FT   BINDING         65..66
FT                   /ligand="substrate"
FT   Optional; Condition: S-G
FT   ACT_SITE        71
FT                   /note="Proton donor/acceptor"
FT   Condition: D
FT   BINDING         19
FT                   /ligand="substrate"
FT   Condition: H
FT   BINDING         23
FT                   /ligand="substrate"
FT   Condition: K
FT   BINDING         98
FT                   /ligand="substrate"
FT   Condition: H
XX
Size: 110-210;
Related: None;
Template: P0A731;
Scope:
 Archaea
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Divergent SYNY3 with an unknown C-terminal domain not shown in alignment
 and not used in size range
XX
# Revision 1.22 2023/06/01
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