AC   MF_00561;
DC   Protein; auto
TR   HAMAP; MF_00561; -; 1; level=0
XX
Names: ADP_PFKinase
XX
ID   K6PF
DE   RecName: Full=ADP-specific phosphofructokinase;
DE            EC=2.7.1.146;
DE   AltName: Full=ADP-dependent phosphofructokinase;
DE            Short=ADP-Pfk;
GN   Name=pfkC;
XX
CC   -!- FUNCTION: Catalyzes the phosphorylation of fructose 6-phosphate to
CC       fructose 1,6-bisphosphate using ADP as the phosphate donor.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ADP + beta-D-fructose 6-phosphate = AMP + beta-D-fructose 1,6-
CC         bisphosphate + H(+); Xref=Rhea:RHEA:20105, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:57634, ChEBI:CHEBI:456215,
CC         ChEBI:CHEBI:456216; EC=2.7.1.146;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC       Note=Binds 1 Mg(2+) ion per subunit.;
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkC family.
XX
DR   Pfam; PF04587; ADP_PFK_GK; 1; trigger=no
DR   PROSITE; PS51255; ADPK; 1; trigger=yes
DR   NCBIfam; TIGR02045; P_fruct_ADP; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Kinase
KW   Glycolysis
KW   Magnesium
KW   Metal-binding
XX
GO   GO:0016773; F:phosphotransferase activity, alcohol group as acceptor
GO   GO:0006096; P:glycolytic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: K6PF_METJA (Q58999)
FT   ACT_SITE        442
FT                   /note="Proton acceptor"
FT   Condition: D
FT   BINDING         272
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: E
FT   BINDING         302
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: E
FT   BINDING         442
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
XX
Size: 440-505;
Related: MF_00809;
Template: Q58999; Q9V2Z7;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.29 2023/06/01
//