AC MF_00562; DC Protein; auto TR HAMAP; MF_00562; -; 1; level=0 XX Names: Deacylase_DtdA XX ID DTDA DE RecName: Full=D-aminoacyl-tRNA deacylase; DE EC=3.1.1.96; GN Name=dtdA; XX CC -!- FUNCTION: D-aminoacyl-tRNA deacylase with broad substrate specificity. CC By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, CC this enzyme counteracts the toxicity associated with the formation of CC D-aminoacyl-tRNA entities in vivo. CC -!- CATALYTIC ACTIVITY: CC Reaction=a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+); CC Xref=Rhea:RHEA:13953, Rhea:RHEA-COMP:10123, Rhea:RHEA-COMP:10124, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:59871, CC ChEBI:CHEBI:78442, ChEBI:CHEBI:79333; EC=3.1.1.96; CC -!- CATALYTIC ACTIVITY: CC Reaction=glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala); CC Xref=Rhea:RHEA:53744, Rhea:RHEA-COMP:9657, Rhea:RHEA-COMP:13640, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57305, CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78522; EC=3.1.1.96; CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Note=Binds 2 Zn(2+) ions per subunit.; CC -!- SUBUNIT: Monomer. CC -!- SIMILARITY: Belongs to the DtdA deacylase family. XX DR Pfam; PF04414; tRNA_deacylase; 1; trigger=no DR PIRSF; PIRSF016210; UCP016210; 1; trigger=no XX KW Hydrolase KW Metal-binding KW Zinc XX GO GO:0008270; F:zinc ion binding GO GO:0016788; F:hydrolase activity, acting on ester bonds GO GO:0051499; F:D-aminoacyl-tRNA deacylase activity GO GO:0019478; P:D-amino acid catabolic process XX FT None XX Size: 237-524; Related: None; Template: Q9V2R8; Scope: Archaea Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: Divergent HALSA not shown in alignment XX # Revision 1.29 2022/01/06 //